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QS 21

Known as: Stimulon QS-21 Adjuvant, QS-21 Adjuvant, QS21 
A purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential immunoadjuvant activity. When co-administered… 
National Institutes of Health

Related topics

Related topics

10 relations
Cytotoxic T-LymphocytesGM2-KLH vaccine/QS21KSA glycoprotein/QS21KSA-KLH conjugate vaccine/QS21

Broader (2)

Immunologic AdjuvantsSaponins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants.
QS-7-Api is an exceedingly potent immuno-adjuvant isolated from the bark of Quillaja saponaria. It is significantly less toxic… 
Highly Cited
2007
Highly Cited
2007
Safety trial using the Leishmune vaccine against canine visceral leishmaniasis in Brazil.
Highly Cited
2002
Highly Cited
2002
T-cell responses against tyrosinase 368-376(370D) peptide in HLA*A0201+ melanoma patients: randomized trial comparing incomplete Freund's adjuvant, granulocyte macrophage colony-stimulating factor…
We conducted a randomized trial in HLA*A0201+ patientswith American Joint Committee on Cancer stage III or IV melanoma immunized… 
Highly Cited
2002
Highly Cited
2002
The level of protection against rotavirus shedding in mice following immunization with a chimeric VP6 protein is dependent on the route and the coadministered adjuvant.
Highly Cited
1999
Highly Cited
1999
Effects of different adjuvants on rotavirus antibody responses and protection in mice following intramuscular immunization with inactivated rotavirus.
Highly Cited
1999
Highly Cited
1999
Preclinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice.
Highly Cited
1999
Highly Cited
1999
Vaccination with carbohydrate peptide mimotopes promotes anti-tumor responses
Tumor-associated carbohydrate (TAC) antigens are important targets in cancer vaccine efforts. Carbohydrates are, however… 
Highly Cited
1998
Highly Cited
1998
QS-21 and QS-7: purified saponin adjuvants.
QS-21 and QS-7 are two adjuvant-active saponins that can be obtained in high purity from Quillaja saponaria Molina extracts. QS… 
1998
1998
Immunogenicity of synthetic conjugates of Lewisy oligosaccharide with proteins in mice: towards the design of anticancer vaccines
Abstract Many human carcinomas overexpress the Lewisy (Ley) blood-group epitope [Fucα1→2Galβ1→4 (Fucα1→3)GlcNAcβ1→3Gal-]. With a… 
Highly Cited
1998
Highly Cited
1998
Antibodies against GD2 ganglioside can eradicate syngeneic cancer micrometastases.
After 10 years of clinical trials in patients with advanced cancer, monoclonal antibodies (mAbs) against cell surface antigens… 
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