QS 21

Known as: Stimulon QS-21 Adjuvant, QS-21 Adjuvant, QS21 
A purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential immunoadjuvant activity. When co-administered… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
The immunostimulants 3-O-desacyl-4'-monophosphoryl lipid A (MPL) and the saponin QS-21 are part of licensed or candidate vaccines… (More)
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Review
2011
Review
2011
One of the most widely used and potent immunological adjuvants is a mixture of soluble triterpene glycosides purified from the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AN1792 (beta-amyloid [Abeta]1-42) immunization reduces Abeta plaque burden and preserves cognitive function in APP… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Alzheimer disease (AD) is characterized by progressive cerebral atrophy that may be measured using MRI. Reported are… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND AD is characterized by cerebral deposition of beta-amyloid plaques with amyloid beta-peptide (Abeta) 42 as the major… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE Vaccine alternatives to high-dose interferon alfa-2b therapy (HDI), the current standard adjuvant therapy for high-risk… (More)
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Highly Cited
2000
Highly Cited
2000
Our objective was to determine whether an immune response can be generated against MUC1 peptide and against tumor cell MUC1 after… (More)
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Review
1999
Review
1999
Currently, aluminum salts and MF59 are the only vaccine adjuvants approved for human use. With the development of new-generation… (More)
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1998
1998
QS-21 is a purified immunological adjuvant derived from a natural source, the bark of the tree Quillaja saponaria. It is a water… (More)
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Highly Cited
1995
Highly Cited
1995
The cell surface gangliosides GM2, GD2, and GD3 are often overexpressed in malignant melanoma. We have shown previously that… (More)
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