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Pyrithioxin

Known as: Piritinol, Pyrithioxine, 4-Pyridinemethanol, 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl- ) 
A neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
National Institutes of Health

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15 relations

Narrower (7)

BonifenEncephabolEnerbolJPC 80
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

pyridine

Papers overview

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2007
2007
REVERSAL OF SODIUM NITRITE INDUCED IMPAIRMENT OF SPONTANEOUS ALTERATION BY ALOE VERA GEL: INVOLVEMENT OF CHOLINERGIC SYSTEM
Summary The present investigation was aimed at determining the spectrum of activity of aloe vera gel on CNS. Effect of aloe vera… 
1986
1986
Contribution to the search for vigilance-indicative EEG variables. Results of a controlled, double-blind study with pyritinol in elderly patients with symptoms of mental dysfunction.
We used a clinical pharmacological model to test pyritinol versus placebo in patients with mental deficiency and a clinical… 
1983
1983
Antiinflammatory and immunostimulant activities of six sulphur compounds--four benzenesulphonates, levamisole, and pyritinol hydrochloride--assayed in mouse cell activation studies.
The effect of a phlogogenic agent and of six sulphur compounds on peritoneal macrophages, spleen B lymphocytes, and von Kupffer… 
Review
1983
Review
1983
[Captopril induced lichenoid eruption].
The authors report three cases of Captopril induced lichenoid eruption, already unmentionned, as far as they know. This cutaneous… 
1980
1980
A placebo-controlled study of pyritinol ('Encephabol') in dementia.
: A double-blind, placebo-controlled trial was carried out on 40 patients suffering from moderately advanced dementia. The… 
1978
1978
[Two cases of superficial pemphigus induced by pyritinol (author's transl)].
Pyritinol is presently prescribed in rhumatoid polyarthritis because of its structural analogy to D-penicillamin. Only benign… 
1977
1977
Effect of pyritinol-GCl on blood flow and oxidative metabolism of the brain in patients with dementia.
In order to test whether and in what way pyritinon-HCl affects cerebral blood flow and oxidative metabolism in patients with… 
1976
1976
[Clinical picture of Central European tick-borne encephalitis (author's transl)].
Tick-borne encephalitis is transmitted by the tick ixodes ricinus. After the second world war an increase in the number of cases… 
1976
1976
A new model of active avoidance conditioning adequate for pharmacological studies.
A model of rapid learning (active avoidance conditioning), using rats, is described which induces retention depending on the… 
1973
1973
Photosensitive dermatitis due to pyritinol.
Lichen planus-like photosensitive dermatitis due to pyritinol hydrochloride occurred in a 62-year-old man. Pigmentation…