Pyrimidones
National Institutes of Health
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α-Pyrones and pyrimidones are common structural motifs in natural products and bioactive compounds. They also display…
A series of fused pyrimidone derivatives of 4-pyrones was synthesized by conversion of the acetates of Baylis−Hillman adducts…
A new series of the title compounds incorporated into diverse N and O heterocyclic moieties of pharmacoavailability as anti…
N-Protected-(aminoacyl)benzotriazoles 1a-e, g, i, j, 1a'-c' convert heterocyclic amines of the following series: thiazoles (3a…
A Facile and efficient method for the synthesis of 4-hetryl substituted β-lactams 1 have been reported from substituted…
N-Protected (Z)-3-(arylamino)-2,3-dehydroalanine esters 5 and 10 were prepared in one step from methyl (Z)-2-acylamino-3…
[reaction: see text] An efficient one-step synthesis of 2,4-diazabicyclo[4.2.0]octa-1(6),2-dien-5-ones 3 from methyl 2-chloro-2…
UV light induces DNA lesions which are mutagenic in mammalian cells. We used simian virus 40 tsB201 (unable to produce viral…