J. Svete

Publications624
h-index24
Citations2,999
Highly Influential Citations9
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STEREOSELECTIVE 1,3-DIPOLAR CYCLOADDITIONS TO (S)-1-BENZOYL-3-(CYANOMETHYLIDENE)-5-(METHOXYCARBONYL)PYRROLIDIN-2-ONE
Utilisation of chiral enaminones and azomethine imines in the synthesis of functionalised pyrazoles
Chiral enaminones, derived from commercially available enantipure starting materials, such as (+)-camphor and α-amino acids, were employed in cycloconcensation reactions with hydrazine derivatives to…
Synthesis of heterocycles from alkyl 3-(dimethylamino)propenoates and related enaminones.
Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease.
We have identified tryptophan-based selective nanomolar butyrylcholinesterase (BChE) inhibitors. They are defined according to their chemical modularity, novel binding mode revealed by five solved…
Synthesis and biological evaluation of 7-(aminoalkyl)pyrazolo[1,5-a]pyrimidine derivatives as cathepsin K inhibitors.
The Synthesis of Aplysinopsins, Meridianines, and Related Compounds
Diethyl N,N‐Dimethylaminomethylenemalonate in the Synthesis of Fused Heterocyclic Systems.
Dispersion of Nanoparticles in Different Media Importantly Determines the Composition of Their Protein Corona
TLDR
The results suggest that the protein corona composition is a complex function of the constituents present in the media used for dispersion of NPs, which implies the relevance of dispersion media used to prepare NPs.
In vitro assessment of potential bladder papillary neoplasm treatment with functionalized polyethyleneimine coated magnetic nanoparticles.
TLDR
Viability assays showed that bovine serum albumin coating reduced NPs cytotoxicity immediately after 3 h exposure and that such NPs were more toxic to urothelial papillary neoplasm cells compared to normal porcine u rothelial cells at 50 μg/ml NPs concentration, however, 24 h after exposure, bovines serumalbumin functionalized NPs had similar effect on viability of both cell lines.
Recent Advances in the Synthesis of Polysubstituted 3-Pyrazolidinones
An account of recent developments in the field of 3-pyrazolidinone chemistry is given with special focus on the synthesis and transformations of 5-substituted…
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