Pyrazolones

Known as: Pyrazolones [Chemical/Ingredient] 
Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
05101519502016

Papers overview

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2016
2016
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common cause of hypersensitivity reactions, with pyrazolones the most… (More)
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2011
2011
Amyotrophic lateral sclerosis (ALS) is an orphan neurodegenerative disease currently without a cure. Mutations in copper/zinc… (More)
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2010
2010
BACKGROUND Human enterovirus 71 (HEV71) causes outbreaks of life-threatening diseases throughout the world. The genesis of these… (More)
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2009
2009
Two series of novel rigid pyrazolone derivatives were synthesized and evaluated as inhibitors of Mycobacterium tuberculosis (MTB… (More)
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2009
2009
BACKGROUND Pyrazolones are a major cause of immediate IgE-mediated reactions to drugs in many countries. OBJECTIVE The aim of… (More)
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2006
2006
The risk of agranulocytosis associated with the use of pyrazolone drugs at therapeutical doses and for short periods of time has… (More)
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2003
2003
BACKGROUND Propyphenazone (1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one; PP) is a nonsteroidal anti… (More)
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1999
1999
BACKGROUND In Germany about 20000 new cases of urothelial cancer (UC) and about 7500 deaths from bladder cancer alone occur each… (More)
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1995
1995
There has been concern about the role of analgesics in the development of renal-cell cancer, although a few studies have reported… (More)
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1980
1980
  • S. Okonek
  • British journal of clinical pharmacology
  • 1980
1 About 50 severe or fatal (mostly accidental) cases of intoxication in children by pyrazolones have been reported in the German… (More)
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