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Pyrazolones

Known as: Pyrazolones [Chemical/Ingredient] 
Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.
National Institutes of Health

Papers overview

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2016
2016
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common cause of hypersensitivity reactions, with pyrazolones the most… Expand
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Review
2012
Review
2012
SummaryIn many countries, the pyrazolone derivatives, which include dipyrone, antipyrine, aminopyrine and propyphenazone, are… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently involved groups of medicines in… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Pyrazolones are a major cause of immediate IgE-mediated reactions to drugs in many countries. OBJECTIVE The aim of… Expand
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2009
2009
Two series of novel rigid pyrazolone derivatives were synthesized and evaluated as inhibitors of Mycobacterium tuberculosis (MTB… Expand
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2006
2006
The risk of agranulocytosis associated with the use of pyrazolone drugs at therapeutical doses and for short periods of time has… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Propyphenazone (1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one; PP) is a nonsteroidal anti… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND We assessed the reliability of basophil activation test (FAST) and sulphidoleukotriene production (CAST) in the in… Expand
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1999
1999
BACKGROUND In Germany about 20000 new cases of urothelial cancer (UC) and about 7500 deaths from bladder cancer alone occur each… Expand
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Review
1980
Review
1980
1 Propyphenazone 220 mg was administered orally to volunteers. Maximum plasma concentrations between 1.5 microgram/ml and 3.5… Expand
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