Skip to search formSkip to main contentSkip to account menu

Pyrazolones

Known as: Pyrazolones [Chemical/Ingredient] 
Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (13)

4,4-dimethylpyrazolone4-vinyl-3-pyrazolidinoneCC 401L.N. 1520
In BloodPyrazolones, analgesics and antipyreticsagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The catalytic asymmetric synthesis of CF3-containing spiro-oxindole-pyrrolidine-pyrazolone compounds through squaramide-catalyzed 1,3-dipolar cycloaddition.
Pharmaceutically important compounds were synthesized through the organocatalytic 1,3-dipolar cycloaddition reaction. In the… 
2019
2019
Metal-free cyclization of unsaturated hydrazones for the divergent assembly of pyrazolones and pyrazolines.
An oxidative cyclization of β,γ-unsaturated hydrazones for the divergent assembly of pyrazolones and pyrazolines under metal-free… 
2019
2019
Lewis base catalyzed regioselective cyclization of allene ketones or α-methyl allene ketones with unsaturated pyrazolones.
A nitrogen-containing Lewis base catalyzed highly regioselective [4 + 2] cycloaddition of allene ketones or α-methyl allene… 
2017
2017
One-flask synthesis of pyrazolone thioethers involving catalyzed and uncatalyzed thioetherification pathways of pyrazolones.
A one-flask thioetherification of pyrazolones has been demonstrated by transforming several pyrazolones to their corresponding 4… 
2016
2016
Asymmetric chlorination of 4-substituted pyrazolones catalyzed by natural cinchona alkaloid.
A natural quinidine-catalyzed asymmetric chlorination of 4-substituted pyrazolones is developed, affording products with a… 
2015
2015
Mechanistic insight into conjugated N-N bond cleavage by Rh(III)-catalyzed redox-neutral C-H activation of pyrazolones.
Density functional theory (DFT) calculations have been performed to investigate the detailed mechanism of Rh(III)-catalyzed redox… 
Review
2014
Review
2014
Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition.
Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types. These receptors… 
2012
2012
Synthesis and Antimicrobial Evaluation of Novel Pyrazolones and Pyrazolone Nucleosides
The synthesis of a novel series of 4-arylhydrazono-5-methyl-1,2-dihydropyrazol-3-ones 4a–h, and their N 2-alkyl and acyclo… 
2001
2001
Solid‐Phase Synthesis of Substituted Pyrazolones from Polymer‐Bound β‐Keto Esters
Polymer-bound acetoacetate 3 was γ-mono- and γ-dialkylated, as well as α-monoalkylated, to give 6, 9, and 13, respectively… 
1951
1951
The synthesis and ultra-violet spectra of some pyrazolones.
Twenty-five pyrazolones were prepared by reacting mono- or disubstituted cyanoacetic esters with hydrazine, phenylhydrazine and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)