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CC 401

Known as: CC-401, CC401 cpd 
A second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrazolones

Papers overview

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2015
2015
The c‐Jun N‐terminal kinase inhibitor SP600125 inhibits human cytomegalovirus replication
Human cytomegalovirus (HCMV) is an opportunistic pathogen that causes severe diseases in congenitally infected newborns and… 
2014
2014
477 Jab1/Csn5: a new player driving the resistance to HER2-targeted therapies for breast cancer
2014
2014
Abstract 488: Inhibition of JNK signaling sensitizes hypoxic colon cancer cells to DNA-damaging agents
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA BACKGROUND: We have shown that hypoxia induces signaling… 
2006
2006
In Chronic Lymphocytic Leukemia, Zap70 Identifies a Survival Pathway Signal Cascade Involving p85 PI-3-Kinase, CrkL, and Cbl with Syk En Route to JNK1 and bcl-2.
Bcl-2 expression is high in CLL and this appears to participate in disease progression. Zap70 expression is a poor prognostic… 
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