Pyrantel

Known as: Pyrantel [Chemical/Ingredient], Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)- 
A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It… (More)
National Institutes of Health

Papers overview

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2009
2009
BACKGROUND Intestinal parasitic nematodes such as hookworms, Ascaris lumbricoides, and Trichuris trichiura are amongst most… (More)
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2009
2009
The molecular mechanism of resistance to nicotinic agonist anthelmintics such as pyrantel and levamisole in nematodes of medical… (More)
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2008
2008
Resistance of the canine hookworm Ancylostoma caninum to anthelmintic therapy with pyrantel is an emerging problem in canine… (More)
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2004
2004
Three pharmacological subtypes of cholinergic receptors have been distinguished in Ascaris suum using a muscle contraction assay… (More)
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Highly Cited
2003
Highly Cited
2003
Knowledge about the metabolism of anti-parasitic drugs (APDs) will be helpful in ongoing efforts to optimise dosage… (More)
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2000
2000
Resistance to the anthelmintics pyrantel ((E)-1,4,5, 6-tetrahydro-1-methyl-2-[2-(2thienyl)ethenyl]pyrimidine) and levamisole ((S… (More)
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Review
1999
Review
1999
In recent years significant progress has been made in understanding the ecology, epidemiology and related morbidity and… (More)
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Highly Cited
1997
Highly Cited
1997
Preliminary studies indicated that single-dose (500 mg) mebendazole gave disappointing results in the treatment of hookworm… (More)
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1993
1993
Experiments were carried out in the hamster to compare the relative susceptibility of Necator americanus and Ancylostoma… (More)
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1970
1970
1. The pharmacological properties of an anthelmintic, pyrantel, and some of its analogues have been described and compared with… (More)
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