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Pyrantel

Known as: Pyrantel [Chemical/Ingredient], Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)- 
A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
  • J. Matthews
  • International journal for parasitology. Drugs and…
  • 2014
  • Corpus ID: 2570599
Graphical abstract 
Highly Cited
2014
Highly Cited
2009
Highly Cited
2009
Background Intestinal parasitic nematodes such as hookworms, Ascaris lumbricoides, and Trichuris trichiura are amongst most… Expand
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Highly Cited
2006
Highly Cited
2006
Pharmacological experiments on Ascaris suum have demonstrated the presence of three (N‐, L‐, and B‐) subtypes of cholinergic… Expand
Highly Cited
2003
Highly Cited
2003
ObjectiveKnowledge about the metabolism of anti-parasitic drugs (APDs) will be helpful in ongoing efforts to optimise dosage… Expand
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Review
2002
Review
2002
  • R. Kaplan
  • Veterinary research
  • 2002
  • Corpus ID: 17941439
Suppressive anthelmintic treatment strategies originally designed to control Strongylus vulgaris in horses were extremely… Expand
Review
1999
Review
1999
In recent years significant progress has been made in understanding the ecology, epidemiology and related morbidity and… Expand
Review
1997
Review
1997
  • R. Martin
  • Veterinary journal
  • 1997
  • Corpus ID: 44448094
Modes of action of anthelmintic drugs are described. Some anthelmintic drugs act rapidly and selectively on neuromuscular… Expand
Highly Cited
1997
Highly Cited
1997
Preliminary studies indicated that single-dose (500 mg) mebendazole gave disappointing results in the treatment of hookworm… Expand
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Highly Cited
1970
Highly Cited
1970
1 . The pharmacological properties of an anthelmintic, pyrantel, and some of its analogues have been described and compared with… Expand