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Pyrantel

Known as: Pyrantel [Chemical/Ingredient], Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)- 
A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It… Expand
National Institutes of Health

Related topics

Related topics

43 relations
AncylostomiasisAscariasisDrug AllergyEnterobiasis
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Broader (2)

Antinematodal AgentsNeuromuscular Depolarizing Agents

Narrower (10)

CombantrinDrontalExodusLiqui-Vict 2X
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Anthelmintic resistance in equine nematodes
  • J. Matthews
  • International journal for parasitology. Drugs and…
  • 2014
    • Corpus ID: 2570599
Graphical abstract 
Highly Cited
2014
Highly Cited
2014
Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: “The Worminator”
Graphical abstract 
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Highly Cited
2009
Highly Cited
2009
The New Anthelmintic Tribendimidine is an L-type (Levamisole and Pyrantel) Nicotinic Acetylcholine Receptor Agonist
Background Intestinal parasitic nematodes such as hookworms, Ascaris lumbricoides, and Trichuris trichiura are amongst most… Expand
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Highly Cited
2006
Highly Cited
2006
Pharmacology of N‐, L‐, and B‐subtypes of nematode nAChR resolved at the single‐channel level in Ascaris suum
Pharmacological experiments on Ascaris suum have demonstrated the presence of three (N‐, L‐, and B‐) subtypes of cholinergic… Expand
Highly Cited
2003
Highly Cited
2003
Identification of human cytochrome P450s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
ObjectiveKnowledge about the metabolism of anti-parasitic drugs (APDs) will be helpful in ongoing efforts to optimise dosage… Expand
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Review
2002
Review
2002
Anthelmintic resistance in nematodes of horses.
  • R. Kaplan
  • Veterinary research
  • 2002
    • Corpus ID: 17941439
Suppressive anthelmintic treatment strategies originally designed to control Strongylus vulgaris in horses were extremely… Expand
Review
1999
Review
1999
Control strategies for human intestinal nematode infections.
In recent years significant progress has been made in understanding the ecology, epidemiology and related morbidity and… Expand
Review
1997
Review
1997
Modes of action of anthelmintic drugs.
  • R. Martin
  • Veterinary journal
  • 1997
    • Corpus ID: 44448094
Modes of action of anthelmintic drugs are described. Some anthelmintic drugs act rapidly and selectively on neuromuscular… Expand
Highly Cited
1997
Highly Cited
1997
Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali.
Preliminary studies indicated that single-dose (500 mg) mebendazole gave disappointing results in the treatment of hookworm… Expand
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Highly Cited
1970
Highly Cited
1970
Aspects of the pharmacology of a new anthelmintic: pyrantel
1 . The pharmacological properties of an anthelmintic, pyrantel, and some of its analogues have been described and compared with… Expand
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