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Putative Polycomb Group Protein ASXL1

Known as: ASXL1, Additional Sex Combs-Like Protein 1 
Putative Polycomb group protein ASXL1 (1541 aa, ~165 kDa) is encoded by the human ASXL1 gene. This protein may be involved in the modulation of both… 
National Institutes of Health

Papers overview

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2018
2018
Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm, characterized by persistent monocytosis… 
2018
2018
Chapuy, B., Roemer, M.G., Stewart, C., Tan, Y., Abo, R.P., Zhang, L., Dunford, A.J., Meredith, D.M., Thorner, A.R., Jordanova, E… 
2015
2015
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm (MPN) characterized by an increased number of platelets… 
2015
2015
Recent studies suggest that aging-associated inflammation, or "inflammaging", contributes to genetic instability and MDS… 
Highly Cited
2012
Highly Cited
2012
Mutations in the TET2 and ASXL1 genes have been described in approximately 14% and 8% of patients, respectively, with classic… 
2012
2012
Acquired somatic mutations of JAK2 have been reported to play a pivotal role in the pathogenesis of BCR‐ABL1‐negative… 
2012
2012
Clinically, Weaver syndrome is closely related to Sotos syndrome, which is frequently caused by mutations in NSD1. This gene also… 
2011
2011
The BCR-ABL1-negative classic myeloproliferative neoplasms, polycythemia vera (PV), essential thrombocytemia (ET) and primary…