Putative Polycomb Group Protein ASXL1

Known as: ASXL1, Additional Sex Combs-Like Protein 1 
Putative Polycomb group protein ASXL1 (1541 aa, ~165 kDa) is encoded by the human ASXL1 gene. This protein may be involved in the modulation of both… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Several genetic alterations characteristic of leukemia and lymphoma have been detected in the blood of individuals without… (More)
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Highly Cited
2013
Highly Cited
2013
Somatic Addition of Sex Combs Like 1 (ASXL1) mutations occur in 10-30% of patients with myeloid malignancies, most commonly in… (More)
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Highly Cited
2013
Highly Cited
2013
Patient outcome in primary myelofibrosis (PMF) is significantly influenced by karyotype. We studied 879 PMF patients to determine… (More)
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Highly Cited
2013
Highly Cited
2013
High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE Several prognostic scoring systems have been proposed for chronic myelomonocytic leukemia (CMML), a disease in which some… (More)
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Highly Cited
2012
Highly Cited
2012
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute… (More)
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Highly Cited
2011
Highly Cited
2011
Progression of chronic myelogenous leukemia (CML) to accelerated (AP) and blast phase (BP) is because of secondary molecular… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired… (More)
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Review
2010
Review
2010
Myeloproliferative neoplasms (MPNs) originate from genetically transformed hematopoietic stem cells that retain the capacity for… (More)
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Highly Cited
2009
Highly Cited
2009
The myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haematological diseases characterized by ineffective… (More)
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