ASXL1 gene

Known as: Additional Sex Combs Like 1 (Drosophila) Gene, ASXL1, KIAA0978 
This gene may be involved in both transcriptional regulation and chromatin remodeling.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
BACKGROUND The incidence of hematologic cancers increases with age. These cancers are associated with recurrent somatic mutations… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Somatic Addition of Sex Combs Like 1 (ASXL1) mutations occur in 10-30% of patients with myeloid malignancies, most commonly in… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute… (More)
Is this relevant?
Review
2012
Review
2012
The ASXL1 gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein… (More)
  • figure 1
  • table 1
Is this relevant?
Highly Cited
2011
Highly Cited
2011
BACKGROUND Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2011
Highly Cited
2011
PURPOSE To study the incidence and prognostic impact of mutations in Additional sex comb-like 1 (ASXL1) in a large cohort of… (More)
Is this relevant?
Review
2010
Review
2010
Myeloproliferative neoplasms (MPNs) originate from genetically transformed hematopoietic stem cells that retain the capacity for… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
6 Ljunggren HG, Kärre K. In search of the ‘missing self’: MHC molecules and NK cell recognition. Immunol Today 1990; 11: 237–244… (More)
  • table 1
  • figure 1
  • table 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid malignancies, but they have not… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haematological diseases characterized by ineffective… (More)
Is this relevant?