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Purpura, Thrombotic Thrombocytopenic

Known as: Purpura, Thrombotic Thrombocytopenic [Disease/Finding], Disease, Moschkowitz, Thrombopenic Purpura, Thrombotic 
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical… 
National Institutes of Health

Related topics

Related topics

20 relations
ADAMTS13 geneBlood VesselDisseminated Intravascular CoagulationHematopoietic and Lymphoid Cell

Narrower (4)

Congenital Thrombotic Thrombocytopenic PurpuraFamilial Thrombotic Thrombocytopenic PurpuraHemolytic-Uremic SyndromeThrombotic thrombocytopenic purpura, acquired

Broader (3)

Thrombotic MicroangiopathiesVascular Diseasescirculatory disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Methylene blue‐photoinactivated plasma vs. fresh‐frozen plasma as replacement fluid for plasma exchange in thrombotic thrombocytopenic purpura
Background and Objectives  Plasma exchange with fresh‐frozen plasma (FFP) is the treatment of choice in thrombotic… 
Highly Cited
2004
Highly Cited
2004
A randomized phase III trial of DX-8951f (Exatecan Mesylate; DX) and Gemcitabine (GEM) vs. Gemcitabine alone in advanced pancreatic cancer (APC).
4006 BACKGROUND: DX is a novel hexacyclic, water-soluble, topoisomerase-1 inhibitor. DX has single-agent and combination activity… 
Review
1994
Review
1994
The role of heparin in the prevention of extremity and digit necrosis in meningococcal purpura fulminans
In order to gather data regarding the utility of heparin therapy in limiting digit and extremity necrosis resulting from… 
Highly Cited
1988
Highly Cited
1988
Thrombotic Thrombocytopenic Purpura
A 40-year-old obese black woman has had weakness and epigastric pain for several weeks and diarrhea and vomiting for four days… 
Highly Cited
1987
Highly Cited
1987
Deleterious effects of platelet transfusions and recovery thrombocytosis in patients with thrombotic microangiopathy.
Highly Cited
1983
Highly Cited
1983
A monoclonal anti-platelet antibody with decreased reactivity for autoimmune thrombocytopenic platelets.
Two monoclonal anti-platelet antibodies, 3B2 and 8G11, have been raised that are specific for normal human platelets. 3B2 is… 
Highly Cited
1981
Highly Cited
1981
Intravenous prostacyclin in thrombotic thrombocytopenic purpura.
A therapeutic trial of prostacyclin (PGI), was done in a patient with thrombotic thrombocytopenic purpura resistant to treatment… 
Highly Cited
1977
Highly Cited
1977
Elevated platelet-associated IgG in thrombotic thrombocytopenic purpura.
A 41-year--old woman with thrombotic thrombocytopenic purpura (TTP) was treated with prednisone and splenectomy with complete… 
Highly Cited
1966
Highly Cited
1966
Pathology of the cardiac conduction system in thrombotic thrombocytopenic purpura.
Excerpt Thrombotic thrombocytopenic purpura is a fascinating uncommon hematologic disease that is becoming recognized with… 
Highly Cited
1942
Highly Cited
1942
PRIMARY SPLENIC NEUTROPENIA; A NEWLY RECOGNIZED SYNDROME, CLOSELY RELATED TO CONGENITAL HEMOLYTIC ICTERUS AND ESSENTIAL THROMBOCYTOPENIC PURPURA
Excerpt The spleen may no longer be regarded as an organ of complete mystery. Out of ancient and modern superstitious musings and… 
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