Purpura, Thrombotic Thrombocytopenic

Known as: Purpura, Thrombotic Thrombocytopenic [Disease/Finding], Disease, Moschkowitz, Thrombopenic Purpura, Thrombotic 
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical… (More)
National Institutes of Health

Related topics

Related topics

20 relations
ADAMTS13 geneBlood VesselDisseminated Intravascular CoagulationHematopoietic and Lymphoid Cell
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Narrower (4)

Congenital Thrombotic Thrombocytopenic PurpuraFamilial Thrombotic Thrombocytopenic PurpuraHemolytic-Uremic SyndromeThrombotic thrombocytopenic purpura, acquired

Broader (3)

Thrombotic MicroangiopathiesVascular Diseasescirculatory disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Survival and relapse in patients with thrombotic thrombocytopenic purpura.
Survival of patients with thrombotic thrombocytopenic purpura (TTP) improved dramatically with plasma exchange treatment… (More)
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Highly Cited
2010
Highly Cited
2010
How I treat patients with thrombotic thrombocytopenic purpura: 2010.
Thrombotic thrombocytopenic purpura (TTP) is the common name for adults with microangiopathic hemolytic anemia, thrombocytopenia… (More)
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Review
2008
Review
2008
Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura.
Discoveries during the past decade have revolutionized our understanding of idiopathic thrombotic thrombocytopenic purpura (TTP… (More)
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Highly Cited
2003
Highly Cited
2003
ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients.
Initial management of patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is difficult because… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening systemic illness of abrupt onset and unknown cause. Proteolysis… (More)
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Review
2001
Review
2001
Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura.
The term thrombotic microangiopathy (TMA) defines a lesion of vessel wall thickening (mainly arterioles or capillaries… (More)
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Highly Cited
2000
Highly Cited
2000
Thrombotic thrombocytopenic purpura associated with clopidogrel.
BACKGROUND The antiplatelet drug clopidogrel is a new thienopyridine derivative whose mechanism of action and chemical structure… (More)
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Highly Cited
1998
Highly Cited
1998
Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
BACKGROUND Thrombotic thrombocytopenic purpura is a potentially fatal disease characterized by widespread platelet thrombi in the… (More)
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Highly Cited
1998
Highly Cited
1998
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
BACKGROUND Thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome are severe microvascular disorders of platelet… (More)
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Highly Cited
1991
Highly Cited
1991
Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group.
BACKGROUND Thrombotic thrombocytopenic purpura is an uncommon disease with a high mortality rate even with current treatment. The… (More)
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