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Purinergic P1 Receptor Agonists

Known as: Adenosine Receptor Agonists, Purinoceptor Agonists, P1, Agonists, Adenosine Receptor 
Compounds that bind to and stimulate PURINERGIC P1 RECEPTORS.
National Institutes of Health

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16 relations

Narrower (10)

2-(2-phenylethoxy)adenosine2-hexyloxyadenosine8-butylamino-N(6)-cyclopentyladenosine8-butylaminoadenosine
Adenosine Receptor Agonist [EPC]Adenosine Receptor Agonists [MoA]In Bloodaspects of radiation effects

Papers overview

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Highly Cited
2006
Highly Cited
2006
Tachycardia Caused by A2A Adenosine Receptor Agonists Is Mediated by Direct Sympathoexcitation in Awake Rats
Adenosine-induced tachycardia is suggested to be mediated via A2A receptors; however, the exact mechanism for this effect remains… 
Review
2005
Review
2005
Taming the neutrophil: calcium clearance and influx mechanisms as novel targets for pharmacological control
Neutrophils are relatively insensitive to the anti‐inflammatory actions of conventional chemotherapeutic agents, including… 
Highly Cited
2003
Highly Cited
2003
cDNA Microarray Analysis Reveals a Nuclear Factor-κB-Independent Regulation of Macrophage Function by Adenosine
Adenosine is released into the extracellular space from nerve terminals and cells subjected to ischemic stress. This nucleoside… 
Highly Cited
2000
Highly Cited
2000
Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.
Adenosine receptor agonists have cardioprotective, cerebroprotective, and antiinflammatory properties. We report that a… 
Highly Cited
1996
Highly Cited
1996
Adenosine A2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes
AbstractUsing the reverse transcription polymerase chain reaction (RT PCR) we found that human neutrophils express mRNA for both… 
Highly Cited
1993
Highly Cited
1993
Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.
Signal transduction by A1 adenosine receptors was investigated by measuring the modulation by adenosine agonists of guanosine-5… 
Highly Cited
1993
Highly Cited
1993
Inhibition of human monocyte TNF production by adenosine receptor agonists.
Highly Cited
1992
Highly Cited
1992
Excitatory Transmitter Amino Acid Release from the Ischemic Rat Cerebral Cortex: Effects of Adenosine Receptor Agonists and Antagonists
Abstract: The effects of selective adenosine receptor agonists [N6‐cyclopentyladenosine (CPA) and N‐ethylcarboxamidoadenosine… 
Highly Cited
1984
Highly Cited
1984
On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings.
The process by which adenosine receptor agonists inhibit the evoked release of acetylcholine (ACh) was studied at motor nerve… 
Highly Cited
1984
Highly Cited
1984
Effects of adenosine receptor agonists in the isolated, perfused rat kidney.
Two subclasses of adenosine receptors, A1 and A2, have been described. The purpose of these experiments was to determine and… 
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