Prp19 complex

Known as: NTC, Prp19 complex location 
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE Hypoglycemia is associated with increased mortality in hospitalized patients. We investigated the relationship between… (More)
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2012
2012
The ribosomes stalled at the end of non-stop mRNAs must be rescued for productive cycles of cellular protein synthesis… (More)
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Highly Cited
2011
Highly Cited
2011
Many cells die during development, tissue homeostasis, and disease. Dysregulation of apoptosis leads to cranial neural tube… (More)
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Highly Cited
2010
Highly Cited
2010
Protein complexes containing Prp19 play a central role during catalytic activation of the spliceosome, and Prp19 and its related… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The cost of trauma center care is high, raising questions about the value of a regionalized approach to trauma care… (More)
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Highly Cited
2010
Highly Cited
2010
Approximately 80% of breast cancers express the estrogen receptor-α (ERα) and are treated with anti-estrogens. Resistance to… (More)
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2010
2010
BACKGROUND Triage attempts to ensure that severely injured patients are transported to a high-level trauma facility to reduce… (More)
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Review
2008
Review
2008
The Notch signaling pathway constitutes an ancient and conserved mechanism for cell-cell communication in metazoan organisms, and… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Intimate partner violence (IPV) is one of the most common causes of posttraumatic stress disorder (PTSD) in women… (More)
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Highly Cited
2005
Highly Cited
2005
Coupling between transcription and pre-mRNA splicing is a key regulatory mechanism in gene expression. Here, we investigate… (More)
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