Proximal Interphalangeal Joint 3

Known as: PIP3 
A ginglymoid (hinge) synovial joint within the third digit of the hand or foot connecting the proximal and middle phalanges.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We search in this paper for context-specific modes of three-dimensional (3D) cell migration using imaging for… (More)
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Highly Cited
2010
Highly Cited
2010
Despite their low abundance, phosphoinositides are critical regulators of intracellular signaling and membrane… (More)
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Highly Cited
2008
Highly Cited
2008
Excessive activation of G-protein-coupled receptor (GPCR) and receptor tyrosine kinase (RTK) pathways has been linked to prostate… (More)
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Highly Cited
2007
Highly Cited
2007
Chemotaxing neutrophils and Dictyostelium amoebae produce in their plasma membranes the signaling lipid PI(3,4,5)P3 (PIP3) in… (More)
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Highly Cited
2006
Highly Cited
2006
Chemoattractants like f-Met-Leu-Phe (fMLP) induce neutrophils to polarize by triggering divergent signals that promote the… (More)
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Highly Cited
2006
Highly Cited
2006
Phosphatidylinositol-(3,4,5)-trisphosphate (PIP3), a product of phosphatidylinositol 3-kinase, is an important second messenger… (More)
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Highly Cited
2005
Highly Cited
2005
Several pleckstrin-homology (PH) domains with the ability to bind phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5)P3… (More)
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Highly Cited
2004
Highly Cited
2004
Stimulation of cells with various peptide growth factors induces the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3… (More)
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Highly Cited
2002
Highly Cited
2002
The phosphoinositide phosphatase PTEN is mutated in many human cancers. Although the role of PTEN has been studied extensively… (More)
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Review
2001
Review
2001
Protein tyrosine phosphatases (PTPs) are a diverse group of enzymes that contain a highly conserved active site motif, Cys-x5-Arg… (More)
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