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Prothrombin

Known as: Prothrombin [Chemical/Ingredient], Differentiation Reversal Factor, Factor II, Coagulation 
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa… 
National Institutes of Health

Related topics

Related topics

47 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCerebrovascular accidentCoagulants

Broader (3)

Blood Coagulation FactorEnzyme InhibitorsEnzyme Precursors

Narrower (17)

Factor IIaKcentraacarboxy prothrombinacetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study.
2011
2011
Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation.
AIM To examine whether hepatitis C virus (HCV)-infected patients who carry hypercoagulable mutations suffer from increased rates… 
2009
2009
Thromboelastography in patients with cerebral venous thrombosis.
Highly Cited
2008
Highly Cited
2008
Genetic Background of Nontraumatic Osteonecrosis of the Femoral Head in the Korean Population
AbstractMajor thrombophilic mutations have been identified as risk factors for nontraumatic osteonecrosis of the femoral head… 
Highly Cited
2006
Highly Cited
2006
Genetic thrombophilic mutations among couples with recurrent miscarriage.
BACKGROUND Some cases of recurrent first trimester miscarriage (RM)-the loss of three or more consecutive pregnancies at <12… 
2004
2004
Prevalence of Factor V Leiden, Prothrombin G20210A, and MTHFR C677T Mutations in 200 Healthy Jordanians
  • S. EidGhada Rihani
  • American Society for Clinical Laboratory Science
  • 2004
  • Corpus ID: 5705557
Thrombophilia is now considered a multi-causal condition, with interplay of acquired genetic risk factors. In order to estimate… 
2003
2003
Factor V Leiden--the commonest molecular defect in arterial and venous thrombophilia in India.
2002
2002
Prothrombin G20210A is a Bifunctional Gene Polymorphism
Summary The G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the… 
1999
1999
Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations in a Greek population of blood donors
The pathogenesis of venous thrombosis involves the interaction of genetic and environmental factors. In order to estimate the… 
1971
1971
Prothrombal: A New Concentrate of Human Prothrombin Complex for Clinical Use
Summary. There is a great need for a concentrate containing coagulation factors II, VII, IX and X, suitable for the prevention or… 
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