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Prothrombin
Known as:
Prothrombin [Chemical/Ingredient]
, Differentiation Reversal Factor
, Factor II, Coagulation
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A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa…
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National Institutes of Health
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Related topics
Related topics
47 relations
Activated Partial Thromboplastin Time measurement
Blood coagulation
Cerebrovascular accident
Coagulants
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Broader (3)
Blood Coagulation Factor
Enzyme Inhibitors
Enzyme Precursors
Narrower (17)
Factor IIa
Kcentra
acarboxy prothrombin
acetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients
K. Einhaupl
,
J. Stam
,
+4 authors
F. Masuhr
European Journal of Neurology
2010
Corpus ID: 43055578
Background: Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes…
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Highly Cited
2010
Highly Cited
2010
Risk Assessment of Recurrence in Patients With Unprovoked Deep Vein Thrombosis or Pulmonary Embolism: The Vienna Prediction Model
S. Eichinger
,
G. Heinze
,
L. M. Jandeck
,
P. Kyrle
Circulation
2010
Corpus ID: 8793596
Background— Predicting the risk of recurrent venous thromboembolism (VTE) in an individual patient is often not feasible. We…
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Highly Cited
2009
Highly Cited
2009
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study
R. Urbanus
,
B. Siegerink
,
M. Roest
,
F. Rosendaal
,
P. Groot
,
A. Algra
Lancet Neurology
2009
Corpus ID: 12969348
Highly Cited
2004
Highly Cited
2004
Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder.
J. Gris
,
É. Mercier
,
+7 authors
P. Marés
Blood
2004
Corpus ID: 38974
The prospective evaluation of the effect of thromboprophylaxis in women with one unexplained pregnancy loss from the 10th week of…
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Highly Cited
2004
Highly Cited
2004
Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up.
A. Kosch
,
E. Kuwertz-Bröking
,
C. Heller
,
K. Kurnik
,
R. Schobess
,
U. Nowak-Göttl
Blood
2004
Corpus ID: 6357157
The present study was designed to evaluate prothrombotic risk profiles in 59 consecutively recruited white neonates with renal…
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Review
2002
Review
2002
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
C. Lockwood
Obstetrics and Gynecology
2002
Corpus ID: 23930268
Highly Cited
2001
Highly Cited
2001
Frequency and prevention of symptomless deep-vein thrombosis in long-haul flights: a randomised trial
J. Scurr
,
S. Machin
,
Sarah Bailey-King
,
I. Mackie
,
Sally McDonald
,
P. Smith
The Lancet
2001
Corpus ID: 21332456
Highly Cited
2000
Highly Cited
2000
High levels of coagulation factor XI as a risk factor for venous thrombosis.
J. Meijers
,
W. Tekelenburg
,
B. Bouma
,
R. Bertina
,
F. Rosendaal
New England Journal of Medicine
2000
Corpus ID: 23956430
BACKGROUND Factor XI, a component of the intrinsic pathway of coagulation, contributes to the generation of thrombin, which is…
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Highly Cited
1999
Highly Cited
1999
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Ulrike Nowak-Gö
,
Ronald Ttl
,
+5 authors
U. Nowak-Göttl
Blood
1999
Corpus ID: 745565
Ischemic stroke is a rare event in childhood. In approximately one third of cases no obvious underlying cause or disorder can be…
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Highly Cited
1998
Highly Cited
1998
Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.
V. De Stefano
,
P. Chiusolo
,
+6 authors
G. Leone
Blood
1998
Corpus ID: 22788284
The factor II G20210A mutation is a recently identified congenital risk factor for venous thrombosis. Its role in artery disease…
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