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Prothrombin
Known as:
Prothrombin [Chemical/Ingredient]
, Differentiation Reversal Factor
, Factor II, Coagulation
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A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa…
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National Institutes of Health
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Related topics
Related topics
47 relations
Activated Partial Thromboplastin Time measurement
Blood coagulation
Cerebrovascular accident
Coagulants
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Broader (3)
Blood Coagulation Factor
Enzyme Inhibitors
Enzyme Precursors
Narrower (17)
Factor IIa
Kcentra
acarboxy prothrombin
acetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study.
E. Plompen
,
S. Darwish Murad
,
+8 authors
F. Leebeek
Journal of Hepatology
2015
Corpus ID: 5232454
2011
2011
Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation.
N. Maharshak
,
P. Halfon
,
+7 authors
R. Oren
World Journal of Gastroenterology
2011
Corpus ID: 24999464
AIM To examine whether hepatitis C virus (HCV)-infected patients who carry hypercoagulable mutations suffer from increased rates…
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2009
2009
Thromboelastography in patients with cerebral venous thrombosis.
K. Koopman
,
M. Uyttenboogaart
,
+5 authors
J. van der Meer
Thrombosis Research
2009
Corpus ID: 25664720
2008
2008
AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms
A. Miñano
,
A. Ordóñez
,
+9 authors
J. Corral
Haematologica
2008
Corpus ID: 764616
Several studies have shown an effect of AB0 blood group on hemostasis. Findings of this study indicate that non-00 group…
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Highly Cited
2008
Highly Cited
2008
Genetic Background of Nontraumatic Osteonecrosis of the Femoral Head in the Korean Population
J. Chang
,
M. Hur
,
Sang-Soo Lee
,
Jehyun Yoo
,
Kyu Man Lee
Clinical Orthopaedics and Related Research
2008
Corpus ID: 44612689
AbstractMajor thrombophilic mutations have been identified as risk factors for nontraumatic osteonecrosis of the femoral head…
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Highly Cited
2006
Highly Cited
2006
Genetic thrombophilic mutations among couples with recurrent miscarriage.
S. Jivraj
,
R. Rai
,
J. Underwood
,
L. Regan
Human Reproduction
2006
Corpus ID: 36346292
BACKGROUND Some cases of recurrent first trimester miscarriage (RM)-the loss of three or more consecutive pregnancies at <12…
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2004
2004
Prevalence of Factor V Leiden, Prothrombin G20210A, and MTHFR C677T Mutations in 200 Healthy Jordanians
S. Eid
,
Ghada Rihani
American Society for Clinical Laboratory Science
2004
Corpus ID: 5705557
Thrombophilia is now considered a multi-causal condition, with interplay of acquired genetic risk factors. In order to estimate…
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2003
2003
Factor V Leiden--the commonest molecular defect in arterial and venous thrombophilia in India.
R. Ahmed
,
Pawan Gupta
,
M. Kannan
,
V. Choudhry
,
R. Saxena
Thrombosis Research
2003
Corpus ID: 38553577
2002
2002
Prothrombin G20210A is a Bifunctional Gene Polymorphism
A. Carter
,
Mythily Sachchithananthan
,
S. Stasinopoulos
,
F. Maurer
,
R. Medcalf
Thrombosis and Haemostasis
2002
Corpus ID: 7260074
Summary The G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the…
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1999
1999
Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations in a Greek population of blood donors
T. Antoniadi
,
T. Hatzis
,
C. Kroupis
,
E. Economou-Petersen
,
M. Petersen
1999
Corpus ID: 196382376
The pathogenesis of venous thrombosis involves the interaction of genetic and environmental factors. In order to estimate the…
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