Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Prothrombin

Known as: Prothrombin [Chemical/Ingredient], Differentiation Reversal Factor, Factor II, Coagulation 
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa… Expand
National Institutes of Health

Related topics

Related topics

47 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCerebrovascular accidentCoagulants
Expand

Broader (3)

Blood Coagulation FactorEnzyme InhibitorsEnzyme Precursors

Narrower (17)

Factor IIaKcentraacarboxy prothrombinacetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients
Background:  Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes… Expand
Highly Cited
2010
Highly Cited
2010
Risk Assessment of Recurrence in Patients With Unprovoked Deep Vein Thrombosis or Pulmonary Embolism: The Vienna Prediction Model
Background— Predicting the risk of recurrent venous thromboembolism (VTE) in an individual patient is often not feasible. We… Expand
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Highly Cited
2007
Highly Cited
2007
Genetic and Acquired Prothrombotic Risk Factors and Sudden Hearing Loss
Objectives: Idiopathic sudden sensorineural hearing loss (ISSNHL) is a frequently encountered condition, and various pathogenetic… Expand
Highly Cited
2004
Highly Cited
2004
Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder.
The prospective evaluation of the effect of thromboprophylaxis in women with one unexplained pregnancy loss from the 10th week of… Expand
  • table 1
  • table 2
  • table 3
  • table 4
Highly Cited
2004
Highly Cited
2004
Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up.
The present study was designed to evaluate prothrombotic risk profiles in 59 consecutively recruited white neonates with renal… Expand
  • table 1
Review
2003
Review
2003
Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.
BACKGROUND The association between the inherited gene mutations of factor V, prothrombin, and homocysteine metabolism and venous… Expand
  • table I
  • table I
  • table II
  • figure 2
  • figure 1
Highly Cited
2000
Highly Cited
2000
High levels of coagulation factor XI as a risk factor for venous thrombosis.
BACKGROUND Factor XI, a component of the intrinsic pathway of coagulation, contributes to the generation of thrombin, which is… Expand
Highly Cited
1999
Highly Cited
1999
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Ischemic stroke is a rare event in childhood. In approximately one third of cases no obvious underlying cause or disorder can be… Expand
  • table 1
Highly Cited
1998
Highly Cited
1998
Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.
The factor II G20210A mutation is a recently identified congenital risk factor for venous thrombosis. Its role in artery disease… Expand
  • table 1
  • figure 1
Highly Cited
1976
Highly Cited
1976
Role of gamma-carboxyglutamic acid. An unusual protein transition required for the calcium-dependent binding of prothrombin to phospholipid.
  • G. Nelsestuen
  • The Journal of biological chemistry
  • 1976
    • Corpus ID: 42080912
A first order calcium-dependent transition can be monitored by a decrease in the intrinsic fluorescence of the isolated "pro… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE