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Prothrombin

Known as: Prothrombin [Chemical/Ingredient], Differentiation Reversal Factor, Factor II, Coagulation 
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa… 
National Institutes of Health

Related topics

Related topics

47 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCerebrovascular accidentCoagulants

Broader (3)

Blood Coagulation FactorEnzyme InhibitorsEnzyme Precursors

Narrower (17)

Factor IIaKcentraacarboxy prothrombinacetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients
Background:  Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes… 
Highly Cited
2010
Highly Cited
2010
Risk Assessment of Recurrence in Patients With Unprovoked Deep Vein Thrombosis or Pulmonary Embolism: The Vienna Prediction Model
Background— Predicting the risk of recurrent venous thromboembolism (VTE) in an individual patient is often not feasible. We… 
Highly Cited
2009
Highly Cited
2009
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study
Review
2006
Review
2006
EFNS guideline on the treatment of cerebral venous and sinus thrombosis
Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still… 
Highly Cited
2004
Highly Cited
2004
Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder.
The prospective evaluation of the effect of thromboprophylaxis in women with one unexplained pregnancy loss from the 10th week of… 
Review
2002
Review
2002
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
  • C. Lockwood
  • Obstetrics and gynecology
  • 2002
  • Corpus ID: 23930268
Highly Cited
2001
Highly Cited
2001
Frequency and prevention of symptomless deep-vein thrombosis in long-haul flights: a randomised trial
Highly Cited
2000
Highly Cited
2000
High levels of coagulation factor XI as a risk factor for venous thrombosis.
BACKGROUND Factor XI, a component of the intrinsic pathway of coagulation, contributes to the generation of thrombin, which is… 
Highly Cited
1999
Highly Cited
1999
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Ischemic stroke is a rare event in childhood. In approximately one third of cases no obvious underlying cause or disorder can be… 
Highly Cited
1998
Highly Cited
1998
Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.
The factor II G20210A mutation is a recently identified congenital risk factor for venous thrombosis. Its role in artery disease… 
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