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Prothrombin

Known as: Prothrombin [Chemical/Ingredient], Differentiation Reversal Factor, Factor II, Coagulation 
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa… 
National Institutes of Health

Related topics

Related topics

47 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCerebrovascular accidentCoagulants

Broader (3)

Blood Coagulation FactorEnzyme InhibitorsEnzyme Precursors

Narrower (17)

Factor IIaKcentraacarboxy prothrombinacetylcysteinyl-leucyl-glutamyl-glutamyl-prolyl-cysteine methyl ester cyclic disulfide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study.
Review
2012
Review
2012
Abdominal thromboses of splanchnic, renal and ovarian veins.
2009
2009
Thromboelastography in patients with cerebral venous thrombosis.
2008
2008
AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms
Several studies have shown an effect of AB0 blood group on hemostasis. Findings of this study indicate that non-00 group… 
2004
2004
Prevalence of Factor V Leiden, Prothrombin G20210A, and MTHFR C677T Mutations in 200 Healthy Jordanians
  • S. EidGhada Rihani
  • American Society for Clinical Laboratory Science
  • 2004
  • Corpus ID: 5705557
Thrombophilia is now considered a multi-causal condition, with interplay of acquired genetic risk factors. In order to estimate… 
2003
2003
Factor V Leiden--the commonest molecular defect in arterial and venous thrombophilia in India.
2002
2002
Prothrombin G20210A is a Bifunctional Gene Polymorphism
Summary The G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the… 
2000
2000
Prothrombin G20210A Mutation: Is It Associated with Pre-Eclampsia?
Objective: A strong independent association between the prothrombin G20210A gene mutation and pre-eclampsia has been reported in… 
Highly Cited
2000
Highly Cited
2000
Angiotensin-converting enzyme DD genotype, angiotensin type 1 receptor CC genotype, and hyperhomocysteinemia increase first-trimester fetal-loss susceptibility
Complications of pregnancy have been found to be related with thrombophilic polymorphisms that explain about 30% of obstetric… 
1999
1999
Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations in a Greek population of blood donors
The pathogenesis of venous thrombosis involves the interaction of genetic and environmental factors. In order to estimate the… 
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