FAQ

Prothrombin

Known as: Prothrombin [Chemical/Ingredient], Differentiation Reversal Factor, Factor II, Coagulation 
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2018
051019752018

Related topics

Related topics

38 relations
Activated Partial Thromboplastin Time measurementBlood coagulationCerebrovascular accidentClotting factor II assay
(More)

Broader (3)

Blood Coagulation FactorEnzyme InhibitorsEnzyme Precursors

Narrower (8)

Factor IIaKcentraPreconativProthrombin time assay
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Prothrombin
Cerebrovascular accident
Hydrolysis
Homeostasis
physiological aspects
agonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking.
A single cytosine-guanine dinucleotide (CpG) site within coagulation factor II (thrombin) receptor-like 3 (F2RL3) was recently… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2013
2013
The molecular mechanism of mediation of adsorbed serum proteins to endothelial cells adhesion and growth on biomaterials.
To explore molecular mechanism of mediation of adsorbed proteins to cell adhesion and growth on biomaterials, this study examined… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2010
2010
Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension.
Idiopathic pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by pulmonary arteriolar remodeling… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2009
2009
Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin.
Von Willebrand factor-binding protein (VWbp), secreted by Staphylococcus aureus, displays secondary structural homology to the 3… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Ischemic stroke is a rare event in childhood. In approximately one third of cases no obvious underlying cause or disorder can be… (More)
  • table 1
Is this relevant?
1999
1999
Venous thromboembolic disease and the prothrombin, methylene tetrahydrofolate reductase and factor V genes.
The prevalence of the A20210 allele of the prothrombin (PT) gene and the T677 allele of the methylene tetrahydrofolate reductase… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Molecular cloning of a potential proteinase activated receptor.
A DNA sequence encoding a G-protein-coupled receptor was isolated from a mouse genomic library. The predicted protein is similar… (More)
Is this relevant?
1988
1988
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.
Since the antithrombin action of heparin fails to interrupt arterial thrombosis, a mediating role for thrombin (EC 3.4.21.5) in… (More)
Is this relevant?
Highly Cited
1981
Highly Cited
1981
Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.
Perfusion of the myocardium with protein C in the presence of thrombin (EC 3.4.21.5) elicits a potent anticoagulant activity… (More)
Is this relevant?
Highly Cited
1975
Highly Cited
1975
Mitogenic activity of blood components. I. Thrombin and prothrombin.
When added to a culture medium of resting confluent chick embryo fibroblasts in the absence of serum, thrombin (EC 3.4.21.5) is… (More)
Is this relevant?