Prothiaden
National Institutes of Health
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BACKGROUND
The tricyclic antidepressant dothiepin is well established in Europe, but clinical experience with the drug in the…
Data from different analyses of reported deaths from overdose with antidepressants in the U. K. reveal that amitriptyline and…
SUMMARY In a single-blind, randomised, parallel-group study comparing the efficacy and tolerability of dothiepin (50-150 mg per…
Pharmacokinetic and pharmacodynamic studies on dothiepin can be divided into three main areas: radiolabelled studies, single dose…
A group of forty patients who presented to their general practitioner with depression or somatic complaints, which were…
This was a single-blind 4-week parallel group comparative trial in fifty depressed patients. Twenty-five patients received 50 mg…
The Hamilton Rating Scale for Depression is in common use, particularly in durg trials. The authors compared this scale with a…
The study here presented was designed to evaluate the advantages of a once a day dosage of tricyclic anti-depressants as against…
Five healthy volunteers took part in a crossover study which examined the serum concentrations of dothiepin and northiaden after…