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Buprenorphine-related deaths among drug addicts in France: a report on 20 fatalities.
Intravenous injection of crushed tablets, a concomitant intake of psychotropics (especially benzodiazepines), and the high dosage of the BUP formulation available in France appear to be the major risk factors for such fatalities. Expand
Entomotoxicology for the forensic toxicologist: much ado about nothing?
When tested, inter-larvae and inter-site variations of drug concentrations were enormous and not reproducible from one case to another, confirming that arthropod larvae are unreliable for quantitative toxicological analysis. Expand
Fly larvae: a new toxicological method of investigation in forensic medicine.
Five drugs (triazolam, oxazepam, phenobarbital, alimemazine, and clomipramine) were identified and assayed in some tissues of a putrefied cadaver and in the maggots found in the body. Expand
Diatom analysis in victim’s tissues as an indicator of the site of drowning
The results showed that a concordance of the abundance of the diatom taxa in tissues compared to the site of drowning and their distribution relative to one another was 65% in the group where the sites of drowning was known and 35% inthe other group. Expand
Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA.
Ecstasy (3,4-methylenedioxymethylamphetamine; MDMA) is a popular club drug often taken with ethanol (EtOH). We recently found EtOH potentiated the psychomotor effects of MDMA in rats. ThisExpand
HPLC/MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples.
The good performances of this method in terms of both sensitivity and specificity make it a convenient alternative to HPLC/coulometry and GC/MS for the separate analysis of BUP and norBUP in biological samples. Expand
Windows of detection of zolpidem in urine and hair: application to two drug facilitated sexual assaults.
A LC-MS/MS method for the detection of zolpidem in hair was developed to detect this drug after a single dose in possible drug facilitated sexual assaults, demonstrating likely previous drug use in addition to recent exposure associated with a positive blood result. Expand
Ethanol–MDMA interactions in rats: the importance of interval between repeated treatments in biobehavioral tolerance and sensitization to the combination
These findings shed new light on the consequences of EtOH–MDMA, taken together at a nearly normal ambient temperature, both in terms of motivation and potential risks for recreational drug users. Expand
High-performance liquid chromatography coupled to ion spray mass spectrometry for the determination of colchicine at ppb levels in human biofluids.
The HPLC-ISP-MS method shows a good linearity over a concentration range from 5 to 200 ng/ml, making the method convenient for both clinical and forensic purposes. Expand
Neurologic disorders due to brain manganese deposition in a jaundiced patient receiving long-term parenteral nutrition.
This observation is the first demonstration of a relationship between high intracerebral manganese levels, radiologic abnormalities, and neurologic disorders during long-term PN. Expand