Buprenorphine-related deaths among drug addicts in France: a report on 20 fatalities.
Intravenous injection of crushed tablets, a concomitant intake of psychotropics (especially benzodiazepines), and the high dosage of the BUP formulation available in France appear to be the major risk factors for such fatalities.
Entomotoxicology for the forensic toxicologist: much ado about nothing?
When tested, inter-larvae and inter-site variations of drug concentrations were enormous and not reproducible from one case to another, confirming that arthropod larvae are unreliable for quantitative toxicological analysis.
Fly larvae: a new toxicological method of investigation in forensic medicine.
- P. Kintz, B. Godelar, A. Tracqui, P. Mangin, A. Lugnier, A. Chaumont
- MedicineJournal of Forensic Sciences
Five drugs (triazolam, oxazepam, phenobarbital, alimemazine, and clomipramine) were identified and assayed in some tissues of a putrefied cadaver and in the maggots found in the body.
HPLC/MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples.
The good performances of this method in terms of both sensitivity and specificity make it a convenient alternative to HPLC/coulometry and GC/MS for the separate analysis of BUP and norBUP in biological samples.
Diatom analysis in victim’s tissues as an indicator of the site of drowning
- B. Ludes, M. Coste, N. North, S. Doray, A. Tracqui, P. Kintz
- Environmental Science, GeographyZeitschrift für Rechtsmedizin
The results showed that a concordance of the abundance of the diatom taxa in tissues compared to the site of drowning and their distribution relative to one another was 65% in the group where the sites of drowning was known and 35% inthe other group.
Windows of detection of zolpidem in urine and hair: application to two drug facilitated sexual assaults.
Neurologic disorders due to brain manganese deposition in a jaundiced patient receiving long-term parenteral nutrition.
- G. Alves, J. Thiebot, A. Tracqui, T. Delangre, C. Guédon, É. Lerebours
- Medicine, PsychologyJPEN - Journal of Parenteral and Enteral…
This observation is the first demonstration of a relationship between high intracerebral manganese levels, radiologic abnormalities, and neurologic disorders during long-term PN.
Determination of cannabinoids in whole blood by UPLC-MS-MS.
The UPLC-MS-MS method was found to be sensitive, specific, and rapid because it requires no derivatization step, and can be an alternative to gas chromatography-mass spectrometry for the determination of cannabinoids in whole blood.
Ethanol–MDMA interactions in rats: the importance of interval between repeated treatments in biobehavioral tolerance and sensitization to the combination
These findings shed new light on the consequences of EtOH–MDMA, taken together at a nearly normal ambient temperature, both in terms of motivation and potential risks for recreational drug users.
Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA.
- S. B. Hamida, A. Tracqui, J. Cassel
- Medicine, BiologyInternational Journal of Neuropsychopharmacology
- 1 July 2009
Ecstasy (3,4-methylenedioxymethylamphetamine; MDMA) is a popular club drug often taken with ethanol (EtOH). We recently found EtOH potentiated the psychomotor effects of MDMA in rats. This…