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Buprenorphine-related deaths among drug addicts in France: a report on 20 fatalities.

Intravenous injection of crushed tablets, a concomitant intake of psychotropics (especially benzodiazepines), and the high dosage of the BUP formulation available in France appear to be the major risk factors for such fatalities.
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Entomotoxicology for the forensic toxicologist: much ado about nothing?

When tested, inter-larvae and inter-site variations of drug concentrations were enormous and not reproducible from one case to another, confirming that arthropod larvae are unreliable for quantitative toxicological analysis.
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Fly larvae: a new toxicological method of investigation in forensic medicine.

Five drugs (triazolam, oxazepam, phenobarbital, alimemazine, and clomipramine) were identified and assayed in some tissues of a putrefied cadaver and in the maggots found in the body.
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HPLC/MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples.

The good performances of this method in terms of both sensitivity and specificity make it a convenient alternative to HPLC/coulometry and GC/MS for the separate analysis of BUP and norBUP in biological samples.
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Diatom analysis in victim’s tissues as an indicator of the site of drowning

The results showed that a concordance of the abundance of the diatom taxa in tissues compared to the site of drowning and their distribution relative to one another was 65% in the group where the sites of drowning was known and 35% inthe other group.
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Windows of detection of zolpidem in urine and hair: application to two drug facilitated sexual assaults.

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Neurologic disorders due to brain manganese deposition in a jaundiced patient receiving long-term parenteral nutrition.

This observation is the first demonstration of a relationship between high intracerebral manganese levels, radiologic abnormalities, and neurologic disorders during long-term PN.
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Determination of cannabinoids in whole blood by UPLC-MS-MS.

The UPLC-MS-MS method was found to be sensitive, specific, and rapid because it requires no derivatization step, and can be an alternative to gas chromatography-mass spectrometry for the determination of cannabinoids in whole blood.
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Ethanol–MDMA interactions in rats: the importance of interval between repeated treatments in biobehavioral tolerance and sensitization to the combination

These findings shed new light on the consequences of EtOH–MDMA, taken together at a nearly normal ambient temperature, both in terms of motivation and potential risks for recreational drug users.
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Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA.

Ecstasy (3,4-methylenedioxymethylamphetamine; MDMA) is a popular club drug often taken with ethanol (EtOH). We recently found EtOH potentiated the psychomotor effects of MDMA in rats. This…
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