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Protein Structure Initiative
Known as:
PSI
A NIGMS initiative to define the basic protein shapes and to catalog all proteins in terms of these shapes. This project will require the…
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National Institutes of Health
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Highly Cited
2010
Highly Cited
2010
Making membrane proteins for structures: a trillion tiny tweaks
M. Baker
Nature Methods
2010
Corpus ID: 9002938
Researchers try multiple means to get high-quality membrane proteins for X-ray crystallography and nuclear magnetic resonance…
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Review
2010
Review
2010
Advances in protein NMR provided by the NIGMS Protein Structure Initiative: impact on drug discovery.
G. Montelione
,
T. Szyperski
Current opinion in drug discovery & development
2010
Corpus ID: 43015598
Rational drug design relies on the 3D structures of biological macromolecules, with a particular emphasis on proteins. The…
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2010
2010
Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism
C. Bakolitsa
,
Abhinav Kumar
,
+54 authors
I. Wilson
Acta Crystallographica. Section F : Structural…
2010
Corpus ID: 12588038
Structures of the first representatives of PF06684 (DUF1185) reveal a Bacillus chorismate mutase-like fold with a potential role…
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2009
2009
Charting an Unknown Protein Universe
K. Heller
PLoS Biology
2009
Corpus ID: 15743040
OnOn the surface, the protein universe seems dauntingly vast. Driven by the increasingly rapid accumulation of genomic sequences…
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Review
2008
Review
2008
Protein Structure Initiative: Phase 3 or Phase Out
R. Service
Science
2008
Corpus ID: 206579592
1610 C R E D IT S ( T O P T O B O T T O M ): N E W Y O R K S T R U C T U R A L G E N O M IX R E S E A R C H C O N S O R T IU M…
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2008
2008
Powerful fusion: PSI-BLAST and consensus sequences
Dariusz Przybylski
,
B. Rost
Bioinform.
2008
Corpus ID: 11367549
Motivation: A typical PSI-BLAST search consists of iterative scanning and alignment of a large sequence database during which a…
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2007
2007
Protein structure space is much more than the sum of its folds
B. Honig
Nature Structural &Molecular Biology
2007
Corpus ID: 6764665
VOLUME 14 NUMBER 6 JUNE 2007 NATURE STRUCTURAL & MOLECULAR BIOLOGY To the Editor: A recent editorial in Nature Structural…
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2006
2006
Inhibition of infectious human immunodeficiency virus type 1 virions via lentiviral vector encoded short antisense RNAs.
Shuo Gu
,
J. Ji
,
James Kim
,
J. Yee
,
J. Rossi
Oligonucleotides
2006
Corpus ID: 30061740
During the life cycles of most retroviruses and lentiviruses, dimerization and packaging of two copies of viral genomic RNA is…
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2006
2006
SPINE: Structural Proteomics in Europe - The best of both worlds
D. Stuart
,
E. Jones
,
K. Wilson
,
S. Daenke
2006
Corpus ID: 11481399
Division of Structural Biology, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, England, and York…
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Review
1998
Review
1998
Class‐directed structure determination: Foundation for a protein structure initiative
T. Terwilliger
,
G. Waldo
,
T. Peat
,
J. Newman
,
K. And
,
J. Berendzen
Protein Science
1998
Corpus ID: 6970249
The recent sequencing of many complete genomes, combined with the development of methods that allow rapid structure determination…
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