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Protein Structure Initiative

Known as: PSI 
A NIGMS initiative to define the basic protein shapes and to catalog all proteins in terms of these shapes. This project will require the… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome
Given the recent successes in determining membrane-protein structures, we explore the tractability of determining representatives… 
2012
2012
The Protein Structure Initiative: achievements and visions for the future
The Protein Structure Initiative (PSI) was established in 2000 by the National Institutes of General Medical Sciences with the… 
Highly Cited
2010
Highly Cited
2010
Making membrane proteins for structures: a trillion tiny tweaks
  • M. Baker
  • Nature Methods
  • 2010
  • Corpus ID: 9002938
Researchers try multiple means to get high-quality membrane proteins for X-ray crystallography and nuclear magnetic resonance… 
Review
2010
Review
2010
Structural classification of proteins and structural genomics: new insights into protein folding and evolution
This review article surveys the protein structures determined by Joint Center for Structural Genomics and published in this… 
Review
2009
Review
2009
PSI-2: structural genomics to cover protein domain family space.
2008
2008
Homology-based modeling of 3D structures of protein-protein complexes using alignments of modified sequence profiles.
Review
2007
Review
2007
Structural genomics of protein phosphatases
The New York SGX Research Center for Structural Genomics (NYSGXRC) of the NIGMS Protein Structure Initiative (PSI) has applied… 
Review
2007
Review
2007
Towards fully automated structure-based function prediction in structural genomics: a case study.
Review
2005
Review
2005
New York-Structural GenomiX Research Consortium (NYSGXRC): A Large Scale Center for the Protein Structure Initiative
Structural GenomiX, Inc. (SGX), four New York area institutions, and two University of California schools have formed the New… 
Review
1998
Review
1998
Class‐directed structure determination: Foundation for a protein structure initiative
The recent sequencing of many complete genomes, combined with the development of methods that allow rapid structure determination… 
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