Protein Phosphatase Inhibitor

Any substance that inhibits a protein phosphatase, especially those that inhibit the serine/threonine protein phosphatases 1 and 2A, enzymes that… (More)
National Institutes of Health

Papers overview

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2006
2006
Protein phosphatases have very recently emerged as important targets for chemical biology and medicinal chemistry research, and… (More)
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Highly Cited
2004
Highly Cited
2004
Ionizing radiation induces autophosphorylation of the ataxia-telangiectasia mutated (ATM) protein kinase on serine 1981; however… (More)
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Highly Cited
2001
Highly Cited
2001
Recent work has shown substantial alterations in NMDA receptor subunit expression, assembly, and phosphorylation in the dopamine… (More)
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Highly Cited
2001
Highly Cited
2001
Raf-1 activation is a complex process which involves plasma membrane recruitment, phosphorylation, protein-protein and lipid… (More)
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Highly Cited
1998
Highly Cited
1998
The regional selectivity and mechanisms underlying the toxicity of the serine/threonine protein phosphatase inhibitor okadaic… (More)
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Highly Cited
1992
Highly Cited
1992
Extracellular deposition of the beta/A4 amyloid peptide is a characteristic feature of the brain in patients with Alzheimer… (More)
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Highly Cited
1991
Highly Cited
1991
Okadaic acid, a specific and potent inhibitor of protein phosphatases 2A and 1, was tested for its effect on the morphology of a… (More)
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1991
1991
The antibiotic, tautomycin, was found to be a potent inhibitor of protein phosphatases and equally effective for the type-1 and… (More)
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Highly Cited
1989
Highly Cited
1989
Okadaic acid is a polyether derivative of 38-carbon fatty acid1, and is implicated as the causative agent of diarrhetic shellfish… (More)
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Highly Cited
1984
Highly Cited
1984
The neurotransmitter dopamine has been demonstrated by biochemical1, histochemical2 and immunocytochemical3,4 techniques to be… (More)
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