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Protein Phosphatase Inhibitor

Any substance that inhibits a protein phosphatase, especially those that inhibit the serine/threonine protein phosphatases 1 and 2A, enzymes that… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
N-Methyl-D-Aspartic acid suppresses Akt activity through protein phosphatase in retinal ganglion cells.
PURPOSE To investigate the relationship between Akt activity and retinal ganglion cell (RGC) death induced by N-Methyl-D-Aspartic… 
Highly Cited
2003
Highly Cited
2003
Molecular Characterization of Ypi1, a Novel Saccharomyces cerevisiae Type 1 Protein Phosphatase Inhibitor*
The Saccharomyces cerevisiae open reading frame YFR003c encodes a small (155-amino acid) hydrophilic protein that we identified… 
2002
2002
Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons
Highly Cited
1998
Highly Cited
1998
Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein.
The U1, U2, U4/U6, and U5 small nuclear ribonucleoproteins (snRNPs) are subunits of splicing complexes that remove introns from… 
Highly Cited
1995
Highly Cited
1995
Multiple second messenger systems act sequentially to mediate rolipram-induced prolongation of prostaglandin E2-induced mechanical hyperalgesia in the rat
Highly Cited
1992
Highly Cited
1992
Effects of okadaic acid, a protein phosphatase inhibitor, on glucocorticoid receptor-mediated enhancement.
The effects of okadaic acid (OA), a protein phosphatase inhibitor, on transcriptional enhancement activity of rat glucocorticoid… 
1992
1992
Modulation of neutrophil activation by okadaic acid, a protein phosphatase inhibitor.
We determined the effects of okadaic acid (OA), a specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A), on protein… 
1992
1992
Changes in the metaphase transit times and the pattern of sister chromatid separation in stamen hair cells of Tradescantia after treatment with protein phosphatase inhibitors.
Stamen hair cells from the spiderwort plant, Tradescantia virginiana, exhibit remarkably predictable metaphase transit times… 
Highly Cited
1977
Highly Cited
1977
Specificity of a protein phosphatase inhibitor from rabbit skeletal muscle.
A hear-stable protein, which is a specific inhibitor of protein phosphatase-III, was purified 700-fold from skeletal muscle by a… 
Highly Cited
1975
Highly Cited
1975
Inactivation of rabbit muscle phosphorylase phosphatase by cyclic AMP-dependent kinas.
Partially purified rabbit skeletal muscle phosphorylase phosphatase (EC 3.1.3.17; phosphoprotein phosphohydrolase) was… 
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