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Protein Degradation, Metabolic

Known as: Protein Degradation, Protein Turnover, protein catabolism 
The normal "downside" of protein steady state metabolism in cells, involving conjugation, transport, oxidation, and proteolysis; not to be confuse… 
National Institutes of Health

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ADAM-TS9 protein, humanADAMTS9 geneCTSH geneCTSH wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade
The ubiquitin-proteasome pathway is involved in intracellular protein turnover, and its function is crucial to cellular… 
Highly Cited
2003
Highly Cited
2003
Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by autophagy
Biochemical and functional studies have demonstrated major histocompatibility complex (MHC) class II‐restricted presentation of… 
Highly Cited
2001
Highly Cited
2001
Proteasome-mediated Glucocorticoid Receptor Degradation Restricts Transcriptional Signaling by Glucocorticoids*
Ligand-dependent down-regulation of the glucocorticoid receptor (GR) has been shown to limit hormone responsiveness, but the… 
Highly Cited
1998
Highly Cited
1998
Functional Domains of the α1 Catalytic Subunit of the AMP-activated Protein Kinase*
The AMP-activated protein kinase is a heterotrimeric enzyme, important in cellular adaptation to the stress of nutrient… 
Highly Cited
1996
Highly Cited
1996
The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover
The 26S proteasome is an essential proteolytic complex that is responsible for degrading proteins conjugated with ubiquitin. It… 
Review
1992
Review
1992
Role of the calpain system in muscle growth.
Highly Cited
1981
Highly Cited
1981
Effect of exercise on protein turnover in man.
1. We have investigated the effects of moderate long-term exercise on protein turnover in fed man by measuring the extent of… 
Highly Cited
1977
Highly Cited
1977
The influence of immobilization and stretch on protein turnover of rat skeletal muscle.
1. Changes in muscle size have been studied as a function of time after immobilization and in relation to the functional length… 
Highly Cited
1976
Highly Cited
1976
A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Purification from porcine muscle.
Ca2+-activated Z-disk-removing activity in the P0-40 crude muscle extracts described by Busch et al. (Busch, W. A., Stromer, M. H… 
Highly Cited
1975
Highly Cited
1975
Skeletal-muscle growth and protein turnover.
Because of turnover, protein synthesis and breakdown can each be involved in the regulation of the growth of tissue protein. To… 
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