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The ubiquitin–26S proteasome system at the nexus of plant biology
  • R. Vierstra
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
  • 1 June 2009
Plants, like other eukaryotes, rely on proteolysis to control the abundance of key regulatory proteins and enzymes. Strikingly, genome-wide studies have revealed that the ubiquitin-26S proteasomeExpand
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The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis
The covalent attachment of ubiquitin is an important determinant for selective protein degradation by the 26S proteasome in plants and animals. The specificity of ubiquitination is often controlledExpand
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The ubiquitin 26S proteasome proteolytic pathway.
Much of plant physiology, growth, and development is controlled by the selective removal of short-lived regulatory proteins. One important proteolytic pathway involves the small protein ubiquitinExpand
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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
The ubiquitin-dependent proteolytic pathway plays a major role in selective protein degradation. Ubiquitination of proteins requires the sequential action of the ubiquitin-activating enzyme (E1),Expand
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Autophagic Nutrient Recycling in Arabidopsis Directed by the ATG8 and ATG12 Conjugation Pathways1
Autophagy is an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lyticExpand
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The Small Ubiquitin-like Modifier (SUMO) Protein Modification System in Arabidopsis
Smallubiquitin-like modifier (SUMO) is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter theirExpand
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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The APG8/12-activating Enzyme APG7 Is Required for Proper Nutrient Recycling and Senescence in Arabidopsis thaliana *
The vacuole/lysosome serves an important recycling function during starvation and senescence in eukaryotes via a process called autophagy. Here bulk cytosolic constituents and organelles becomeExpand
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The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins.
  • R. Vierstra
  • Biology, Medicine
  • Trends in plant science
  • 1 March 2003
Plants use a repertoire of methods to control the level and activity of their constituent proteins. One method, whose prominence is only now being appreciated, is selective protein breakdown by theExpand
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A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome
Phytochromes are red/far-red light photoreceptors that direct photosensory responses across the bacterial, fungal and plant kingdoms. These include photosynthetic potential and pigmentation inExpand
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