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Protein C Inhibitor

Known as: Activated Protein C Inhibitor, Antitrypsin, Plasma Serine Protease Inhibitor 
Plasma serine protease inhibitor (406 aa, ~46 kDa) is encoded by the human SERPINA5 gene. This protein is involved in the regulation of serine… 
National Institutes of Health

Related topics

Related topics

15 relations
Genes, RegulatorIn BloodProcess of secretionRegulation of Proteolysis

Broader (2)

Plasminogen InactivatorsSerine Proteinase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Inactivation of tryptic activity by a human-derived strain of Bacteroides distasonis in the large intestines of gnotobiotic rats and mice
Tryptic activity disappeared and trypsin was no longer detected with an antitrypsin antiserum in the large intestines of… 
1988
1988
Purification and characterization of proteases secreted by transforming schistosomula of Schistosoma mansoni.
1988
1988
Interactions among stimulated human polymorphonuclear leucocytes, released elastase and bronchial antileucoprotease.
1. We investigated the effect of stimulated human polymorphonuclear leucocytes (PMN's) on both the antitrypsin and anti-elastase… 
1988
1988
The possible utility of steroids in the prevention of relapses of Crohn's disease in remission. A preliminary study.
In Crohn's disease, prednisone is believed to be ineffective for relapse prevention. Because all patients with Crohn's Disease… 
Highly Cited
1985
Highly Cited
1985
Antitrypsin and N-acetyl-beta-D-glucosaminidase as markers of mastitis in a herd of Ayshire cows.
Microplate analyzers for N-acetyl-beta-D-glucosaminidase (NAGase) and antitrypsin in milk were high-capacity systems for… 
Highly Cited
1973
Highly Cited
1973
Design, construction, and two applications for an automated flow-cell polarization fluorometer with digital read out: enzyme-inhibitor (antitrypsin) assay and antigen-antibody (insulin-insulin…
We have constructed and automated a flow cell polarization fluorometer and demonstrated two specific clinical applications of… 
Highly Cited
1972
Highly Cited
1972
Sequential changes of the plasma protein pattern in inoculation hepatitis.
22 plasma proteins were followed in inoculation hepatitis for two months after onset of icterus. Increased plasma ai-antitrypsin… 
1971
1971
Smoking and chronic obstructive lung disease in alpha-1-antitrypsin deficiency.
Similar spectra of chronic obstructive lung disease were observed in eight patients with severe and 21 with intermediate alpha1… 
Highly Cited
1967
Highly Cited
1967
Studies on the elastase-serum protein interaction. I. Molecular identity of the inhibitors in human serum and direct demonstration of inhibitor-elastase complexes by zone and immunoelectrophoresis.
1967
1967
α2-Macroglobulin as Progressive Antithrombin
FOR several years we have been interested in the anti-protease activity of human α2-macroglobulin (α2M)1–5. The antitrypsin and… 
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