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Protein AF1q

Known as: AF1Q, MLLT11 
Protein AF1q (90 aa, ~10 kDa) is encoded by the human MLLT11 gene. This protein is involved in the regulation of mitochondrial homeostasis.
National Institutes of Health

Related topics

Related topics

6 relations
Genes, RegulatorMLLT11 geneMLLT11 wt AllelePositive Regulation of Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Recombinant expression and purification of AF1q and its interaction with T-cell Factor 7.
2019
2019
AF1q inhibited T cell attachment to breast cancer cell by attenuating Intracellular Adhesion Molecule-1 expression
Aim: To investigate whether AF1q, overexpressed in metastatic cells compared with the primary tumor cells, plays a pivotal role… 
2018
2018
Abstract 499: MicroRNA-411 downregulation promotes tumorigenesis and inhibits chemotherapy sensitivity by upregulating MLLT11 expression in human bladder cancer
2017
2017
Abstract 3969: AF1q/Mllt11 regulates the expression of intercellular adhesion molecule-1 in breast cancer
Intercellular adhesion molecule-1 (ICAM-1) is a cell surface glycoprotein in the immunoglobulin superfamily. ICAM-1 expression is… 
2015
2015
High expression of AF1q is an adverse prognostic factor in multiple myeloma patients treated with autologous stem cell transplantation
2011
2011
MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML
MLLT11, an MLL fusion partner, is a poor prognostic biomarker for paediatric acute myeloid leukaemia (AML), adult normal… 
2011
2011
AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.
The mechanisms regulating the emergence of BM prothymocytes remain poorly characterized. Genome-wide transcriptome analyses… 
Review
2011
Review
2011
Analysis of differential diagnostic gene expression profiles in uterine leiomyoma and leiomyosarcoma
2009
2009
The AML Prognostic Marker, AF1q, Is Directly Regulated by MiR-29b.
Abstract 2603 Poster Board II-579 We have consistently shown that elevated expression of AF1q, an MLL fusion partner, is a poor… 
2008
2008
AF1q enhances doxorubicin induced apoptosis through mitochondrial apoptotic pathway.
AACR Annual Meeting-- Apr 12-16, 2008; San Diego, CA 2691 AF1q (ALL1-fused gene chromosome 1q) is an oncogenic factor involved… 
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