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Prorenin

Known as: Cryorenin, Renin, Big, Big Renin 
National Institutes of Health

Related topics

Related topics

2 relations
Prorenin:ACnc:Pt:Plas:Qn

Broader (1)

Renin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Functional Significance of Prorenin Internalization in the Rat Heart
Intracardiac renin is considered to be involved in the pathogenesis of cardiac hypertrophy, fibrosis, and myocardial infarction… 
Highly Cited
2002
Highly Cited
2002
Prorenin-Induced Myocyte Proliferation: No Role for Intracellular Angiotensin II
Cardiomyocytes bind, internalize, and activate prorenin, the inactive precursor of renin, via a mannose 6-phosphate receptor… 
Review
1999
Review
1999
Is there a local renin-angiotensin system in the heart?
Highly Cited
1999
Highly Cited
1999
Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.
Highly Cited
1996
Highly Cited
1996
Clinical validation of renin monoclonal antibody-based sandwich assays of renin and prorenin, and use of renin inhibitor to enhance prorenin immunoreactivity.
Newly developed IRMAs to measure the plasma concentrations of renin and prorenin were validated for clinical use and compared… 
Highly Cited
1990
Highly Cited
1990
Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct.
Highly Cited
1983
Highly Cited
1983
Asynchronous changes in prorenin and renin secretion after captopril in patients with renal artery stenosis.
An assay of plasma prorenin was developed in which the conversion to renin occurred under apparently optimal conditions. Some… 
Highly Cited
1983
Highly Cited
1983
The biosynthetic pathway of renin in mouse submandibular gland.
Highly Cited
1977
Highly Cited
1977
Plasma Prorenin in Normal, Hypertensive, and Anephric Subjects and Its Effect on Renin Measurements
We have previously shown that a cryoactivatable inactive form of renin, which we have tentatively termed prorenin, occurs in… 
Highly Cited
1975
Highly Cited
1975
“Prorenin” in Human Plasma?: METHODOLOGICAL AND PHYSIOLOGICAL IMPLICATIONS
An increase in plasma renin activity was demonstrated in plasma from normal subjects and most patients with essential… 
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