Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Renin

Known as: Renin Precursor, Renal, renins, Renin [Chemical/Ingredient] 
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Objective To investigate the mechanism of tissue uptake of renin. Design Angiotensin peptide formation in tissues is dependent on… Expand
Review
1992
Review
1992
  • F. Suzuki
  • Nihon rinsho. Japanese journal of clinical…
  • 1992
  • Corpus ID: 872137
Renin is a key enzyme in the renin-angiotensin system (RAS) which controls the blood pressure and electrolyte balance. By… Expand
Highly Cited
1988
Highly Cited
1988
We have isolated the renin gene from a Sprague-Dawley rat genomic library and determined its complete nucleotide sequence. The… Expand
Highly Cited
1987
Highly Cited
1987
Renin (EC 3.4.23.15) is an aspartyl protease that cleaves its only known substrate, angiotensinogen, to release the vasopressor… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Review
1984
Review
1984
The Ren-1 locus of mice encodes the protease renin, which with converting enzyme processes angiotensinogen to the potent… Expand
  • figure 1
  • figure 2
  • figure 3
Highly Cited
1984
Highly Cited
1984
A model has been constructed using computer graphics for human renin based on the sequence derived from that of the gene and the… Expand
Highly Cited
1983
Highly Cited
1983
The primary structure of human renin precursor has been deduced from its cDNA sequence. A library of cDNA clones was constructed… Expand
  • figure 1
  • figure 3
  • figure 4
Highly Cited
1980
Highly Cited
1980
With the objective of clarifying the nature of renin-like activity in the brain, we have devised methods to distinguish true… Expand
Review
1976
Review
1976
Enzymes, similar to kidney renin, are present in extrarenal tissue of most mammals; they hydrolyze angiotensinogen to form… Expand
Highly Cited
1974
Highly Cited
1974
  • G. W. Boyd
  • Circulation research
  • 1974
  • Corpus ID: 42590525
Two interconvertible renins were isolated from extracts of the pig renal cortex at neutral pH and shown to be protein-bound… Expand