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Propoxyphene Hydrochloride

Known as: Propoxyphene Hydrochloride [Chemical/Ingredient], alpha-d-Propoxyphene Hydrochloride, propoxyphene hcl 
The hydrochloride salt form of the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent… Expand
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

DarvonDistalgesic
Drug AllergyOpioid Agonists [MoA]PainPregnancy
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Papers overview

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Highly Cited
2011
Highly Cited
2011
The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults
Methods: We devised a propensity-matched cohort analysis that used health care utilization data collected from January 1, 1996… Expand
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Highly Cited
2010
Highly Cited
2010
The comparative safety of opioids for nonmalignant pain in older adults.
BACKGROUND Severe nonmalignant pain affects a large proportion of adults. Optimal treatment is not clear, and opioids are an… Expand
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Highly Cited
2007
Highly Cited
2007
Is there a role for tamsulosin in shock wave lithotripsy for renal and ureteral calculi?
PURPOSE We evaluated the effect of the alpha-blocker tamsulosin on stone clearance, analgesic requirements and steinstrasse in… Expand
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Highly Cited
2006
Highly Cited
2006
The Associations Between Severity of Early Postoperative Pain, Chronic Postsurgical Pain and Plasma Concentration of Stable Nitric Oxide Products After Breast Surgery
In this study, we compared the effects of two analgesic regimens on perioperative nitric oxide index (NOx) and the likelihood of… Expand
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2006
2006
Propoxyphene use and risk for hip fractures in older adults.
BACKGROUND Published guidelines have identified propoxyphene as an inappropriate medication for use in aged patients. It is no… Expand
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Highly Cited
1991
Highly Cited
1991
A controlled trial of propoxyphene and naltrexone in patients with tourette's syndrome
To investigate the effect of drugs acting on the endogenous opioid system, we studied 10 adults with Tourette's syndrome who… Expand
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Highly Cited
1978
Highly Cited
1978
Analgesic activity of ibuprofen (Motrin) in postoperative oral surgical pain.
The effectiveness of 400 and 800 mg. of ibuprofen was compared to that of 650 mg. of aspirin, 65 mg. of propoxyphene HCl, and… Expand
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1971
1971
Pulmonary edema associated with propoxyphene intoxication.
In three consecutive cases of severe, rapid intoxication with propoxyphene hydrochloride (Darvon), pulmonary edema was present… Expand
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1971
1971
A comparative analgesia study of propoxyphene hydrochloride, propoxyphene napsylate, and placebo.
Abstract A total of 342 patients with postoperative or fracture pain were divided into 7 groups and were treated with one of the… Expand
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1971
1971
The fate of radiocarbon-labeled propoxyphene in rat, dog, and human.
Abstract Propoxyphene N -demethylation is the primary initial metabolic step in the rat. Ester hydrolysis also occurs. A large… Expand
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