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Propoxyphene Hydrochloride

Known as: Propoxyphene Hydrochloride [Chemical/Ingredient], alpha-d-Propoxyphene Hydrochloride, propoxyphene hcl 
The hydrochloride salt form of the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent… 
National Institutes of Health

Related topics

Related topics

7 relations

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DarvonDistalgesic
Drug AllergyOpioid Agonists [MoA]PainPregnancy
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults
Highly Cited
2007
Highly Cited
2007
Is there a role for tamsulosin in shock wave lithotripsy for renal and ureteral calculi?
Highly Cited
2006
Highly Cited
2006
The Associations Between Severity of Early Postoperative Pain, Chronic Postsurgical Pain and Plasma Concentration of Stable Nitric Oxide Products After Breast Surgery
In this study, we compared the effects of two analgesic regimens on perioperative nitric oxide index (NOx) and the likelihood of… 
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Review
2006
Review
2006
Propoxyphene (dextropropoxyphene): a critical review of a weak opioid analgesic that should remain in antiquity.
Propoxyphene (dextropropoxyphene) is a synthetic weak opioid introduced into the United States in 1957. It is most frequently… 
Highly Cited
1978
Highly Cited
1978
Analgesic activity of ibuprofen (Motrin) in postoperative oral surgical pain.
The effectiveness of 400 and 800 mg. of ibuprofen was compared to that of 650 mg. of aspirin, 65 mg. of propoxyphene HCl, and… 
Highly Cited
1971
Highly Cited
1971
Pulmonary edema associated with propoxyphene intoxication.
In three consecutive cases of severe, rapid intoxication with propoxyphene hydrochloride (Darvon), pulmonary edema was present… 
Highly Cited
1971
Highly Cited
1971
Concentration of propoxyphene in human plasma following oral, intramuscular, and intravenous administration.
Abstract Propoxyphene hydrochloride was administered po, im, and iv to normal human volunteers. Included in the cross-over study… 
Highly Cited
1971
Highly Cited
1971
The fate of radiocarbon-labeled propoxyphene in rat, dog, and human.
Abstract Propoxyphene N -demethylation is the primary initial metabolic step in the rat. Ester hydrolysis also occurs. A large… 
Review
1970
Review
1970
Propoxyphene hydrochloride. A critical review.
A review of the published literature on propoxyphene hydrochloride was undertaken to determine if the wide popularity of the drug… 
1964
1964
PROPOXYPHENE HYDROCHLORIDE POISONING. REPORT OF THE FIRST FATALITY.
PROPOXYPHENE HYDROCHLORIDE (Darvon) has become a widely used analgesic with toxic properties that have been previously noted in… 
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