Propoxyphene Hydrochloride

Known as: Propoxyphene Hydrochloride [Chemical/Ingredient], alpha-d-Propoxyphene Hydrochloride, propoxyphene hcl 
The hydrochloride salt form of the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent… (More)
National Institutes of Health

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DarvonDistalgesic
Drug AllergyOpioid Agonists [MoA]PainPregnancy
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Papers overview

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Highly Cited
2010
Highly Cited
2010
The comparative safety of opioids for nonmalignant pain in older adults.
BACKGROUND Severe nonmalignant pain affects a large proportion of adults. Optimal treatment is not clear, and opioids are an… (More)
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2007
2007
Is there a role for tamsulosin in shock wave lithotripsy for renal and ureteral calculi?
PURPOSE We evaluated the effect of the alpha-blocker tamsulosin on stone clearance, analgesic requirements and steinstrasse in… (More)
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2006
2006
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
In this study, we compared the effects of two analgesic regimens on perioperative nitric oxide index (NOx) and the likelihood of… (More)
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2006
2006
Propoxyphene use and risk for hip fractures in older adults.
BACKGROUND Published guidelines have identified propoxyphene as an inappropriate medication for use in aged patients. It is no… (More)
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Highly Cited
2002
Highly Cited
2002
Electroencephalography and Clinical Neurophysiology 321 Elsevier Publishing Company, Amsterdam -printed in the Netherlands Darvon ® and the Eeg
  • N DARVO, G ANDTHEEE
  • 2002
Dextropropoxyphene hydrochloride (Darvon ®) was synthesized in 1953 (Pohland and Sullivan 1953). Its analgesic effects have been… (More)
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1995
1995
Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
Propoxyphene overdose is known to cause widening of the QRS complex on ECG. We report a case of a 54-year-old female who ingested… (More)
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1991
1991
A controlled trial of propoxyphene and naltrexone in patients with Tourette's syndrome.
To investigate the effect of drugs acting on the endogenous opioid system, we studied 10 adults with Tourette's syndrome who… (More)
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1976
1976
A pharmacokinetic method for designing prolonged-release formulations—Propoxyphene hydrochloride
Many prolonged-release preparations are designed so that a certain fraction is immediately available for absorption upon… (More)
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1975
1975
Propoxyphene and norpropoxyphene tissue concentrations in fatalities associated with propoxyphene hydrochloride and propoxyphene napsylate
Propoxyphene and its major metabolite norpropoxyphene have been determined in blood and liver in 29 cases of death in which… (More)
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1975
1975
Determination of propoxyphene and norpropoxyphene by chemical ionization mass fragmentography.
The kinetics of propoxyphene and its primary metabolite, norpropoxyphene, have been simultaneously re-evaluated in man by using… (More)
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