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Proneural Glioblastoma

A molecular subtype of glioblastoma that is associated with younger age at presentation and is characterized by p53 mutations and PDGFRa… 
National Institutes of Health

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17 relations
AnaplasiaAstrocytesCentral Nervous SystemGrade four rank

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma
Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers… 
2017
2017
Title : A recombinant lentiviral PDGF-driven mouse model of proneural GBM Running title : A novel PDGF-driven mouse model of proneural GBM
© The Author(s) 2017. Published by Oxford University Press on behalf of the Society for NeuroOncology. All rights reserved. For… 
2017
2017
STEM-19. THE TCF12 TRANSCRIPTION FACTOR CONTROLS PRONEURAL GLIOBLASTOMA STEM-LIKE CELLS
2016
2016
Metabolic challenge of proneural glioblastoma cancer stem cell lines does not induce a mesenchymal transformation in vitro
The histologically defined tumor entity glioblastoma (GBM) comprises different molecular subgroups. On a transcriptional level… 
2016
2016
High LGR5 expression in proneural glioblastoma cells contributes to increased self-renewal and invasiveness
Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays… 
2016
2016
PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells.
Glioblastoma is the most aggressive primary brain tumor and responds poorly to currently available therapies. Transcriptomic… 
2015
2015
Quantitative analysis of signaling networks in proneural glioblastoma
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2015. 
2012
2012
Abstract 3343: Upregulation of SOX5 perturbs human glioma cell proliferation and is associated with proneural glioblastoma
Background: The proneural subtype of glioblastoma (GBM) is characterized by PDGFRα alterations. In a retroviral insertional… 
2011
2011
Upregulation of SOX5 can be linked to proneural glioblastoma and perturbs glioma cell proliferation
Upregulation of SOX5 can be linked to proneural glioblastoma and perturbs glioma cell proliferation 
2010
2010
Abstract 113: The TCGA proneural subtype predicts improved clinical outcome for low-grade oligodendrogliomas
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC The Cancer Genome Atlas Project (TCGA) has… 
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