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Proneural Glioblastoma

A molecular subtype of glioblastoma that is associated with younger age at presentation and is characterized by p53 mutations and PDGFRa… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Although tumor-propagating cells can be derived from glioblastomas (GBMs) of the proneural and mesenchymal subtypes, a glioma… Expand
2016
2016
Glioblastomas are the most aggressive primary brain tumor. Despite treatment with surgery, radiation and chemotherapy, these… Expand
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Highly Cited
2015
Highly Cited
2015
PURPOSE The AVAglio (Avastin in Glioblastoma) and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed… Expand
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Highly Cited
2015
Highly Cited
2015
High grade gliomas (HGG) are classified into four subgroups based on transcriptional signatures and phenotypic characteristics… Expand
Highly Cited
2012
Highly Cited
2012
Immune cell infiltration varies widely between different glioblastomas (GBMs). The underlying mechanism, however, remains unknown… Expand
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Highly Cited
2012
Highly Cited
2012
ABSTRACT Proneural NEUROG2 (neurogenin 2 [Ngn2]) is essential for neuronal commitment, cell cycle withdrawal, and neuronal… Expand
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Highly Cited
2012
Highly Cited
2012
Growth factor-mediated proliferation and self-renewal maintain tissue-specific stem cells and are frequently dysregulated in… Expand
Highly Cited
2010
Highly Cited
2010
Patients with glioblastoma (GBM) have variable clinical courses, but the factors that underlie this heterogeneity are not… Expand
Highly Cited
2009
Highly Cited
2009
Epigenetic mechanisms that maintain neurogenesis throughout adult life remain poorly understood. Trithorax group (trxG) and… Expand
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1998
1998
1997). The novel non-bHLH protein encoded by the m4 Neurogenesis by gene of the E(spl)-C (Klä mbt et al., 1989), which is… Expand
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