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Proneural Glioblastoma
A molecular subtype of glioblastoma that is associated with younger age at presentation and is characterized by p53 mutations and PDGFRa…
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National Institutes of Health
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Related topics
Related topics
17 relations
Anaplasia
Astrocytes
Central Nervous System
Grade four rank
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The phenotypes of proliferating glioblastoma cells reside on a single axis of variation.
L. Wang
,
Husam Babikir
,
+13 authors
A. Diaz
Cancer discovery
2019
Corpus ID: 203441527
Although tumor-propagating cells can be derived from glioblastomas (GBMs) of the proneural and mesenchymal subtypes, a glioma…
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2016
2016
Optimization of radiation dosing schedules for proneural glioblastoma
H. Badri
,
K. Pitter
,
E. Holland
,
F. Michor
,
K. Leder
Journal of mathematical biology
2016
Corpus ID: 16785045
Glioblastomas are the most aggressive primary brain tumor. Despite treatment with surgery, radiation and chemotherapy, these…
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Highly Cited
2015
Highly Cited
2015
Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
T. Sandmann
,
R. Bourgon
,
+16 authors
C. Bais
Journal of clinical oncology : official journal…
2015
Corpus ID: 207039503
PURPOSE The AVAglio (Avastin in Glioblastoma) and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed…
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Highly Cited
2015
Highly Cited
2015
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma.
J. Lau
,
Shirin Ilkhanizadeh
,
+7 authors
A. Persson
Cancer research
2015
Corpus ID: 207577049
High grade gliomas (HGG) are classified into four subgroups based on transcriptional signatures and phenotypic characteristics…
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Highly Cited
2012
Highly Cited
2012
The cancer stem cell subtype determines immune infiltration of glioblastoma.
C. Beier
,
Praveen Kumar
,
+14 authors
D. Beier
Stem cells and development
2012
Corpus ID: 9871895
Immune cell infiltration varies widely between different glioblastomas (GBMs). The underlying mechanism, however, remains unknown…
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Highly Cited
2012
Highly Cited
2012
NEUROG2 Drives Cell Cycle Exit of Neuronal Precursors by Specifically Repressing a Subset of Cyclins Acting at the G1 and S Phases of the Cell Cycle
Marine Lacomme
,
L. Liaubet
,
F. Pituello
,
Sophie Bel-Vialar
Molecular and Cellular Biology
2012
Corpus ID: 13732999
ABSTRACT Proneural NEUROG2 (neurogenin 2 [Ngn2]) is essential for neuronal commitment, cell cycle withdrawal, and neuronal…
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Highly Cited
2012
Highly Cited
2012
Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.
Y. Kim
,
E. Kim
,
+11 authors
J. Rich
Genes & development
2012
Corpus ID: 41606988
Growth factor-mediated proliferation and self-renewal maintain tissue-specific stem cells and are frequently dysregulated in…
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Highly Cited
2010
Highly Cited
2010
Presence of Alternative Lengthening of Telomeres Mechanism in Patients With Glioblastoma Identifies a Less Aggressive Tumor Type With Longer Survival
Kerrie L. McDonald
,
J. McDonnell
,
+10 authors
J. Royds
Journal of neuropathology and experimental…
2010
Corpus ID: 25120106
Patients with glioblastoma (GBM) have variable clinical courses, but the factors that underlie this heterogeneity are not…
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Highly Cited
2009
Highly Cited
2009
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
Daniel A. Lim
,
Y. Huang
,
+5 authors
A. Alvarez-Buylla
Nature
2009
Corpus ID: 4343063
Epigenetic mechanisms that maintain neurogenesis throughout adult life remain poorly understood. Trithorax group (trxG) and…
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1998
1998
Regulation of Drosophila Neurogenesis byRNA:RNA Duplexes?
E. Lai
,
J. Posakony
Cell
1998
Corpus ID: 14677993
1997). The novel non-bHLH protein encoded by the m4 Neurogenesis by gene of the E(spl)-C (Klä mbt et al., 1989), which is…
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