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Proneural Glioblastoma

A molecular subtype of glioblastoma that is associated with younger age at presentation and is characterized by p53 mutations and PDGFRa… Expand
National Institutes of Health

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2017
2017
Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers… Expand
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2016
2016
Glioblastomas are the most aggressive primary brain tumor. Despite treatment with surgery, radiation and chemotherapy, these… Expand
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2014
2014
Proneural glioblastoma is defined by an expression pattern resembling that of oligodendrocyte progenitor cells and carries a… Expand
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2014
2014
BACKGROUND Glioblastoma subtypes have been defined based on transcriptional profiling, yet personalized care based on molecular… Expand
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2012
2012
Immune cell infiltration varies widely between different glioblastomas (GBMs). The underlying mechanism, however, remains unknown… Expand
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2012
2012
Proneural NEUROG2 (neurogenin 2 [Ngn2]) is essential for neuronal commitment, cell cycle withdrawal, and neuronal differentiation… Expand
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Highly Cited
2012
Highly Cited
2012
Growth factor-mediated proliferation and self-renewal maintain tissue-specific stem cells and are frequently dysregulated in… Expand
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2010
2010
Patients with glioblastoma (GBM) have variable clinical courses, but the factors that underlie this heterogeneity are not… Expand
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Highly Cited
2009
Highly Cited
2009
Epigenetic mechanisms that maintain neurogenesis throughout adult life remain poorly understood. Trithorax group (trxG) and… Expand
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1998
1998
1997). The novel non-bHLH protein encoded by the m4 Neurogenesis by gene of the E(spl)-C (Klä mbt et al., 1989), which is… Expand
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