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Prolyl Hydroxylase

Known as: Proline Hydroxylase, Hydroxylases, Prolyl, Prolyl Hydroxylases 
Enzymes that specifically hydroxylate PROLINE residues on proteins.
National Institutes of Health

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In BloodProcess of secretionaspects of radiation effectschemical synthesis

Papers overview

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Highly Cited
2009
Highly Cited
2009
Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.
Activation of hypoxia-inducible factors (HIF), responsible for tumor angiogenesis and glycolytic switch, is regulated by reduced… 
Highly Cited
2008
Highly Cited
2008
The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential
Hypoxia is a common feature of solid tumors. The cellular response to hypoxic stress is controlled by a family of prolyl… 
Highly Cited
2005
Highly Cited
2005
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Hypoxia-inducible factor 1 (HIF-1) functions as a master regulator of oxygen homeostasis in metazoan species. HIF-1 mediates… 
Highly Cited
2001
Highly Cited
2001
Characterization of a second carotenoid β-hydroxylase gene from Arabidopsis and its relationship to the LUT1 locus
Xanthophylls are oxygenated carotenoids that perform critical roles in plants. β-carotene hydroxylases (β-hydroxylases) add… 
1986
1986
Immunological properties of monoclonal antibodies to human and rat prolyl 4-hydroxylase.
Monoclonal antibodies to human (8 clones) and rat (12 clones) prolyl 4-hydroxylase [EC 1.14.11.2] were prepared and characterized… 
Highly Cited
1977
Highly Cited
1977
The effect of lymphoma and other neoplasms on hepatic and plasma enzymes of the host rat.
Considerable thymidine kinase and pyrroline-5-carboxylate reductase activities were found in the plasma of rats bearing a… 
1976
1976
Lysyl hydroxylase. Further purification and characterization of the enzyme from chick embryos and chick embryo cartilage.
1975
1975
Radiommunoassay for human and chick prolyl hydroxylases.
A radioimmunoassay is reported for measuring prolyl hydroxylase. The assay is based on the displacement of radioactively-labelled… 
Highly Cited
1972
Highly Cited
1972
Partial purification and characterization of protocollagen lysine hydroxylase from chick embryos.
Highly Cited
1968
Highly Cited
1968
Synthetic polypeptides as substrates and inhibitors of collagen proline hydroxylase.
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