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Prolyl Hydroxylase
Known as:
Proline Hydroxylase
, Hydroxylases, Prolyl
, Prolyl Hydroxylases
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Enzymes that specifically hydroxylate PROLINE residues on proteins.
National Institutes of Health
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Related topics
Related topics
6 relations
In Blood
Process of secretion
aspects of radiation effects
chemical synthesis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.
Olga Aprelikova
,
Olga Aprelikova
,
+7 authors
J. Niederhuber
Cancer Research
2009
Corpus ID: 7188632
Activation of hypoxia-inducible factors (HIF), responsible for tumor angiogenesis and glycolytic switch, is regulated by reduced…
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Highly Cited
2008
Highly Cited
2008
The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential
KangAe Lee
,
J. Lynd
,
S. O'Reilly
,
M. Kiupel
,
J. Mccormick
,
J. LaPres
Molecular Cancer Research
2008
Corpus ID: 13389376
Hypoxia is a common feature of solid tumors. The cellular response to hypoxic stress is controlled by a family of prolyl…
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Highly Cited
2005
Highly Cited
2005
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
J. Baek
,
P. Mahon
,
+6 authors
G. Semenza
Molecules and Cells
2005
Corpus ID: 38862136
Hypoxia-inducible factor 1 (HIF-1) functions as a master regulator of oxygen homeostasis in metazoan species. HIF-1 mediates…
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Highly Cited
2001
Highly Cited
2001
Characterization of a second carotenoid β-hydroxylase gene from Arabidopsis and its relationship to the LUT1 locus
L. Tian
,
D. DellaPenna
Plant Molecular Biology
2001
Corpus ID: 12522318
Xanthophylls are oxygenated carotenoids that perform critical roles in plants. β-carotene hydroxylases (β-hydroxylases) add…
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1986
1986
Immunological properties of monoclonal antibodies to human and rat prolyl 4-hydroxylase.
Y. Bai
,
Y. Muragaki
,
K. Obata
,
K. Iwata
,
A. Ooshima
Journal of Biochemistry (Tokyo)
1986
Corpus ID: 20244058
Monoclonal antibodies to human (8 clones) and rat (12 clones) prolyl 4-hydroxylase [EC 1.14.11.2] were prepared and characterized…
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Highly Cited
1977
Highly Cited
1977
The effect of lymphoma and other neoplasms on hepatic and plasma enzymes of the host rat.
A. Herzfeld
,
O. Greengard
Cancer Research
1977
Corpus ID: 15445801
Considerable thymidine kinase and pyrroline-5-carboxylate reductase activities were found in the plasma of rats bearing a…
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1976
1976
Lysyl hydroxylase. Further purification and characterization of the enzyme from chick embryos and chick embryo cartilage.
L. Ryhänen
Biochimica et Biophysica Acta
1976
Corpus ID: 6316837
1975
1975
Radiommunoassay for human and chick prolyl hydroxylases.
L. Tuderman
,
E. Kuutti
,
K. Kivirikko
European Journal of Biochemistry
1975
Corpus ID: 29621743
A radioimmunoassay is reported for measuring prolyl hydroxylase. The assay is based on the displacement of radioactively-labelled…
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Highly Cited
1973
Highly Cited
1973
Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme.
R. Berg
,
D. Prockop
Journal of Biological Chemistry
1973
Corpus ID: 30283537
Highly Cited
1972
Highly Cited
1972
Partial purification and characterization of protocollagen lysine hydroxylase from chick embryos.
K. Kivirikko
,
D. Prockop
Biochimica et Biophysica Acta
1972
Corpus ID: 44381630
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