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Proglumide

Known as: Xilamide, Proglumide [Chemical/Ingredient], 242 DL 
A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (1)

Anti-Ulcer Agent

Narrower (6)

CR 1372CR 1392Milidlorglumide
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Role of leptin in the control of feeding of goldfish Carassius auratus: interactions with cholecystokinin, neuropeptide Y and orexin A, and modulation by fasting
Review
1989
Review
1989
The role of CCK, caerulein, and CCK antagonists in nociception
Highly Cited
1987
Highly Cited
1987
Role of cholecystokinin in the negative feedback control of pancreatic enzyme secretion in conscious rats.
Highly Cited
1985
Highly Cited
1985
Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates
Highly Cited
1985
Highly Cited
1985
Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin.
Highly Cited
1984
Highly Cited
1984
Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide.
Exogenous cholecystokinin selectively antagonizes opiate analgesia, which suggests that endogenous cholecystokinin may act… 
Highly Cited
1984
Highly Cited
1984
Interactions of cholecystokinin octapeptide and dopamine on nucleus accumbens neurons
Highly Cited
1983
Highly Cited
1983
Proglumide: selective antagonism of excitatory effects of cholecystokinin in central nervous system.
Extracellular single-unit recording techniques were used to test the ability of proglumide to block cholecystokinin-induced… 
Highly Cited
1983
Highly Cited
1983
Characterization and visualization of cholecystokinin receptors in rat brain using [3H]pentagastrin
Highly Cited
1981
Highly Cited
1981
Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.
In dispersed acini from guinea pig pancreas, proglumide (DL-4-benzamido-N, N-dipropylglutaramic acid) and benzotript (N-p… 
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