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Probucol

Known as: Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol), Probucol [Chemical/Ingredient] 
A bis-phenol antioxidant with antilipidemic activity. Probucol inhibits oxidation of low density lipoprotein and lowers the level of cholesterol in… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Highly Cited
2000
Highly Cited
2000
BackgroundThe clinical usefulness of adriamycin is restricted by the development of congestive heart failure. It has been… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Oxidizing metabolites generated at the site of coronary angioplasty can induce chain reactions that may lead to… Expand
Highly Cited
1995
Highly Cited
1995
BACKGROUND The usefulness of adriamycin (ADR), a potent antitumor antibiotic, is limited by the development of life-threatening… Expand
Highly Cited
1995
Highly Cited
1995
BACKGROUND Patients with coronary artery disease and abnormalities of serum lipids often have endothelial vasodilator dysfunction… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND The potential usefulness of adriamycin (ADR) is restricted because of its cardiotoxic side effects. Since free… Expand
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Highly Cited
1991
Highly Cited
1991
Incubation of cocultures of human aortic endothelial (HAEC) and smooth muscle cells (HASMC) with LDL in the presence of 5-10… Expand
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Highly Cited
1987
Highly Cited
1987
In this study, we questioned whether in vivo probucol could prevent the progression of atherosclerosis in homozygous Watanabe… Expand
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Highly Cited
1987
Highly Cited
1987
It has been postulated that low density lipoprotein (LDL) becomes fully atherogenic only if it first undergoes oxidative… Expand
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Highly Cited
1986
Highly Cited
1986
Previous studies have established that low density lipoprotein (LDL) incubated with endothelial cells (EC) undergoes extensive… Expand
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