Probenecid

Known as: Probenecid [Chemical/Ingredient], Probenecid acid, Benzoic acid, 4-((dipropylamino)sulfonyl)- 
A benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule… (More)
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (3)

2-nitroprobenecidBenemidProbecid
AspirinColchicine / ProbenecidDiureticsDrug Allergy
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Broader (5)

Gout SuppressantsPharmaceutical AdjuvantsSulfonamide Anti-Infective AgentsSulfonamides
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Papers overview

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Highly Cited
2008
Highly Cited
2008
Probenecid, a gout remedy, inhibits pannexin 1 channels.
Probenecid is a well-established drug for the treatment of gout and is thought to act on an organic anion transporter, thereby… (More)
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Highly Cited
2006
Highly Cited
2006
High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid.
BACKGROUND Allopurinol has been shown to improve endothelial function in chronic heart failure. This study aimed to establish its… (More)
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Highly Cited
2005
Highly Cited
2005
Efficient aggregation of encrypted data in wireless sensor networks
Wireless sensor networks (WSNs) are ad-hoc networks composed of tiny devices with limited computation and energy capacities. For… (More)
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Highly Cited
2005
Highly Cited
2005
Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells.
Recent experimental and human studies have shown that hyperuricemia is associated with hypertension, systemic inflammation, and… (More)
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Highly Cited
2004
Highly Cited
2004
Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.
The glucuronidation kinetics of the prototypic substrates 4-methylumbelliferone (4MU) and 1-naphthol (1NP) by human UDP… (More)
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Highly Cited
2003
Highly Cited
2003
Enhanced mucosal immunity against Eimeria acervulina in broilers fed a Lactobacillus-based probiotic.
The effect of feeding a Lactobacillus-based probiotic on intestinal intraepithelial lymphocyte (IEL) subpopulations and… (More)
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Highly Cited
2002
Highly Cited
2002
Probabilistic Basis for 2000 SAC Federal Emergency Management Agency Steel Moment Frame Guidelines
This paper presents a formal probabilistic framework for seismic design and assessment of structures and its appl steel moment… (More)
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Highly Cited
1999
Highly Cited
1999
Toward evidence-based medical statistics. 2: The Bayes factor.
In the first of two articles on evidence-based statistics (1), I outlined the inherent difficulties of the standard frequentist… (More)
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Highly Cited
1995
Highly Cited
1995
Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect.
BACKGROUND The usefulness of adriamycin (ADR), a potent antitumor antibiotic, is limited by the development of life-threatening… (More)
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Highly Cited
1974
Highly Cited
1974
Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephalosporin derivatives.
Probenecid may elevate the cerebrospinal fluid (CSF) concentration of penicillin G by inhibiting the excretion of organic acids… (More)
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