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Probenecid

Known as: Probenecid [Chemical/Ingredient], Probenecid acid, Benzoic acid, 4-((dipropylamino)sulfonyl)- 
A benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule… Expand
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (5)

2-nitroprobenecidBenecidBenemidProbecid
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AspirinColchicine / ProbenecidDiureticsDrug Allergy
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Broader (5)

Gout SuppressantsPharmaceutical AdjuvantsSulfonamide Anti-Infective AgentsSulfonamides
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Probenecid, a gout remedy, inhibits pannexin 1 channels.
Probenecid is a well-established drug for the treatment of gout and is thought to act on an organic anion transporter, thereby… Expand
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Highly Cited
2008
Highly Cited
2008
The simplest complete model of choice response time: Linear ballistic accumulation
We propose a linear ballistic accumulator (LBA) model of decision making and reaction time. The LBA is simpler than other models… Expand
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Highly Cited
2005
Highly Cited
2005
Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells.
Recent experimental and human studies have shown that hyperuricemia is associated with hypertension, systemic inflammation, and… Expand
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Highly Cited
2004
Highly Cited
2004
Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.
The glucuronidation kinetics of the prototypic substrates 4-methylumbelliferone (4MU) and 1-naphthol (1NP) by human UDP… Expand
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Highly Cited
2003
Highly Cited
2003
Pathways to emotional dysfunction in first-episode psychosis.
  • M. Birchwood
  • The British journal of psychiatry : the journal…
  • 2003
    • Corpus ID: 8044195
Emotional dysfunction and schizophrenia have long been uncomfortable bedfellows. It was Bleuler who first argued that problems of… Expand
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Highly Cited
2002
Highly Cited
2002
Probabilistic Basis for 2000 SAC Federal Emergency Management Agency Steel Moment Frame Guidelines
This paper presents a formal probabilistic framework for seismic design and assessment of structures and its application to steel… Expand
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Highly Cited
2001
Highly Cited
2001
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is widely used to induce an animal model of Parkinsonism. The conventional… Expand
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Highly Cited
2001
Highly Cited
2001
Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.
The compounds CGP7930 [2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol] and its close analog CGP13501 were identified… Expand
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Highly Cited
1995
Highly Cited
1995
Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect.
BACKGROUND The usefulness of adriamycin (ADR), a potent antitumor antibiotic, is limited by the development of life-threatening… Expand
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Review
1994
Review
1994
Aciclovir. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.
Aciclovir (acyclovir) is a nucleoside analogue with antiviral activity in vitro against the herpes simplex viruses (HSV… Expand
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