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Primary sclerosing cholangitis

Known as: PSC, Sclerosing Cholangitis, cholangitis primary sclerosing 
A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in… 
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
PURPOSE P-glycoprotein is an efflux pump for many drugs including doxorubicin and paclitaxel. This study evaluated the… 
Highly Cited
2001
Highly Cited
2001
PURPOSE To determine the maximum-tolerated dose, pharmacokinetic interaction, and activity of PSC 833 compared with daunorubicin… 
2001
2001
The increased risk for cholangiocarcinoma in primary sclerosing cholangitis (PSC) is well established, but the factors… 
Review
2001
Review
2001
Opinion statementThere is no proven medical therapy for primary sclerosing cholangitis. The goal of management should be… 
Review
2001
Review
2001
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the… 
Highly Cited
1997
Highly Cited
1997
Cathepsin K is a recently identified lysosomal cysteine proteinase that is the major protease responsible for bone resorption and… 
Highly Cited
1996
Highly Cited
1996
The protein encoded by the p53 tumour suppressor gene plays an important part in the regulation of cell growth. Abnormalities of… 
Highly Cited
1982
Highly Cited
1982
Traditional management of patients with primary sclerosing cholangitis (PSC) has included steroids and/or choledochotomy plus… 
Review
1982
Review
1982
The clinical, radiologic and pathologic features of 37 patients diagnosed as having primary sclerosing cholangitis (PSC) were…