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Polycystic kidney disease, type 2

Known as: Polycystic Kidney, Type 2 Autosomal Dominant Disease, APKD2, Polycystic Kidney Disease 2 
Type 2 ADPKD is linked to gene mutation at the PKD2 locus on the long arm of CHROMOSOME 4.
National Institutes of Health

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4 relations
KidneyPKD2 genePolycystic Kidney, Autosomal DominantUrinary system

Papers overview

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Highly Cited
2018
Highly Cited
2018
Prevalence Estimates of Polycystic Kidney and Liver Disease by Population Sequencing.
BACKGROUND Estimating the prevalence of autosomal dominant polycystic kidney disease (ADPKD) is challenging because of age… 
Highly Cited
2017
Highly Cited
2017
Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases.
Data indicate significant phenotypic and genotypic overlap, plus a common pathogenesis, between two groups of inherited disorders… 
Highly Cited
2016
Highly Cited
2016
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
Highly Cited
2003
Highly Cited
2003
Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotype
Highly Cited
1999
Highly Cited
1999
A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
The stereotyped mating behaviour of the Caenorhabditis elegans male is made up of several substeps: response, backing, turning… 
Highly Cited
1999
Highly Cited
1999
Specific association of the gene product of PKD2 with the TRPC1 channel.
The function(s) of the genes (PKD1 and PKD2) responsible for the majority of cases of autosomal dominant polycystic kidney… 
Highly Cited
1998
Highly Cited
1998
Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease
Highly Cited
1998
Highly Cited
1998
Identification of PKDL, a Novel Polycystic Kidney Disease 2-Like Gene Whose Murine Homologue Is Deleted in Mice with Kidney and Retinal Defects*
Polycystin-1 and polycystin-2 are the products ofPKD1 and PKD2, genes that are mutated in most cases of autosomal dominant… 
Highly Cited
1997
Highly Cited
1997
PKD1 interacts with PKD2 through a probable coiled-coil domain
Autosomal dominant polycystic kidney disease (ADPKD) describes a group of at least three genetically distinct disorders with… 
Highly Cited
1997
Highly Cited
1997
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.
PKD1 and PKD2 are two recently identified genes that are responsible for the vast majority of autosomal polycystic kidney disease… 
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