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Polycystic Kidney, Autosomal Dominant

Known as: Polycystic Kidney Disease, Autosomal Dominant, ADPKD, Polycystic Kidney, Autosomal Dominant [Disease/Finding] 
Polycystic kidney disease inherited in an autosomal dominant pattern. Symptoms usually appear at middle age and include abdominal pain, hematuria and… Expand
National Institutes of Health

Related topics

Related topics

14 relations

Broader (1)

Cystic kidney
In BloodKidneyMicrobiologicalPolycystic Kidney Diseases
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Narrower (3)

Medullary Cystic Kidney Disease Type 2Medullary cystic kidney disease 1Polycystic Kidney, Type 1 Autosomal Dominant Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan.
In the past, the treatment of autosomal dominant polycystic kidney disease (ADPKD) has been limited to the management of its… Expand
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Review
2018
Review
2018
Metabolism and mitochondria in polycystic kidney disease research and therapy
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common, potentially lethal, monogenic diseases and is… Expand
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Highly Cited
2014
Highly Cited
2014
Autosomal dominant polycystic kidney disease.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within… Expand
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Highly Cited
2012
Highly Cited
2012
Tolvaptan in patients with autosomal dominant polycystic kidney disease.
BACKGROUND The course of autosomal dominant polycystic kidney disease (ADPKD) is often associated with pain, hypertension, and… Expand
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Highly Cited
2006
Highly Cited
2006
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
Autosomal-dominant polycystic kidney disease (ADPKD) is a common genetic disorder that frequently leads to renal failure… Expand
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Highly Cited
2002
Highly Cited
2002
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia.
Recent evidence has suggested an association between structural and/or functional defects in the primary apical cilium of… Expand
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Highly Cited
1998
Highly Cited
1998
Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease
Germline mutations in PKD2 cause autosomal dominant polycystic kidney disease. We have introduced a mutant exon 1 in tandem with… Expand
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Highly Cited
1996
Highly Cited
1996
PKD2, a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
A second gene for autosomal dominant polycystic kidney disease was identified by positional cloning. Nonsense mutations in this… Expand
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Highly Cited
1996
Highly Cited
1996
The Molecular Basis of Focal Cyst Formation in Human Autosomal Dominant Polycystic Kidney Disease Type I
Autosomal dominant polycystic kidney disease (ADPKD) is a common disease and an important cause of renal failure. It is… Expand
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Highly Cited
1994
Highly Cited
1994
Evaluation of ultrasonographic diagnostic criteria for autosomal dominant polycystic kidney disease 1
Although ultrasound is commonly used for screening subjects at risk of polycystic kidney disease 1 (PKD1), there has been no… Expand
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