Polycystic Kidney Diseases
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The course of autosomal dominant polycystic kidney disease (ADPKD) is often associated with pain, hypertension, and… Expand IntroductionAcute kidney injury (AKI) is a complex disorder for which currently there is no accepted definition. Having a uniform… Expand Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal, monogenic disorder. It is associated with… Expand Frequent complications of polycystic kidney disease include dangerously high blood pressure (hypertension), pain in the back or… Expand Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and… Expand Recent evidence has suggested an association between structural and/or functional defects in the primary apical cilium of… Expand Autosomal recessive polycystic kidney disease (ARPKD) is characterized by dilation of collecting ducts and by biliary dysgenesis… Expand Intraflagellar transport (IFT) is a rapid movement of multi-subunit protein particles along flagellar microtubules and is… Expand A second gene for autosomal dominant polycystic kidney disease was identified by positional cloning. Nonsense mutations in this… Expand bcl-2-/-mice complete embryonic development, but display growth retardation and early mortality postnatally. Hematopoiesis… Expand