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Polyamine Synthesis Inhibition

Polyamine Synthesis Inhibition involves interference with, or restraint of, the activities of biologic molecules or complexes involved in the… 
National Institutes of Health

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EflornithineIsotretinoin

Papers overview

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2014
2014
Abstract 1418: Induction of autophagy and apoptosis with polyamine synthesis inhibition and metformin in human melanoma and colon cancer cells
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA We have previously reported inhibition of cell migration… 
2007
2007
Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats.
BACKGROUND Ethanol exposure and withdrawal during central nervous system development can cause oxidative stress and produce… 
2004
2004
Polyamine Synthesis Inhibition Attenuates Vascular Smooth Muscle Cell Migration
Vascular smooth muscle cell migration, occurring after intimal injury, is a substantial clinical problem in atherosclerosis and… 
1998
1998
Effects of polyamine synthesis inhibition on polyamines, growth and mechanical properties in hypertrophic rat urinary bladder.
The polyamines putrescine, spermidine and spermine, are ubiquitous intracellular metabolites associated with growth and protein… 
1992
1992
Implication of the polyamines in the neurotoxic effects of N-methyl-D-aspartate.
N-Methyl-D-aspartate (NMDA) receptor activation selectively releases the polyamines spermine and spermidine from the rat striatum… 
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