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Isotretinoin
Known as:
Neovitamin a acid
, topical isotretinoin
, Isotretinoina
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A naturally-occurring retinoic acid with potential antineoplastic activity. Isotretinoin binds to and activates nuclear retinoic acid receptors (RARs…
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National Institutes of Health
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Related topics
Related topics
36 relations
Narrower (7)
Accure
Accutane embryopathy
Isotrexin
Oratane
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Accutane
Acne Vulgaris
Drug Allergy
Immunoregulation
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Broader (3)
Dermatologic Agents
Retinoate
Teratogens
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
The use of isotretinoin in acne
A. Layton
Dermato-Endocrinology
2009
Corpus ID: 29930579
Systemic isotretinoin remains the most efficacious treatment for severe acne as well as many cases of more moderate disease that…
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Highly Cited
2003
Highly Cited
2003
Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors.
M. Iwata
,
Yuko Eshima
,
H. Kagechika
International Immunology
2003
Corpus ID: 18317900
The vitamin A metabolite, retinoic acid (RA), affects Th1 and Th2 development. The effect is partly exerted through the…
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Review
2001
Review
2001
Uses and complications of isotretinoin therapy.
Charles N. Ellis
,
Kent J. Krach
Journal of American Academy of Dermatology
2001
Corpus ID: 8671909
Isotretinoin (13-cis-retinoic acid) is a retinoid that has been used over the past 2 decades to treat a wide variety of…
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Highly Cited
1996
Highly Cited
1996
Vitamin A-deficient quail embryos have half a hindbrain and other neural defects
M. Maden
,
E. Gale
,
I. Kostetskii
,
M. Zile
Current Biology
1996
Corpus ID: 17456591
Review
1992
Review
1992
Retinoids in cancer therapy.
Malcolm A. Smith
,
D. Parkinson
,
B. Cheson
,
M. Friedman
Journal of Clinical Oncology
1992
Corpus ID: 24493374
PURPOSE Recent reports of the dramatic antitumor effect of all-trans retinoic acid (RA) in patients with acute promyelocytic…
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Highly Cited
1992
Highly Cited
1992
13-cis-Retinoic Acid Plus Interferon α -2a: Highly Active Systemic Theraphy for Squamous Cell Carcinoma of the Cervix
S. Lippman
,
J. Kavanagh
,
+5 authors
I. Krakoff
1992
Corpus ID: 73105910
BACKGROUND Chemotherapeutic study of cervical squamous cell carcinoma has shown some positive results. Complete plus partial…
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Highly Cited
1990
Highly Cited
1990
Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
A. Oro
,
M. Mckeown
,
R. Evans
Nature
1990
Corpus ID: 4370404
THE vitamin A derivative, retinoic acid, can regulate morpho-genesis and differentiation in vertebrates1,2. Two different sub…
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Highly Cited
1988
Highly Cited
1988
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
M. Suganuma
,
H. Fujiki
,
+7 authors
T. Sugimura
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 21296578
Okadaic acid is a polyether compound of a C38 fatty acid, isolated from a black sponge, Halichondria okadai. Previous studies…
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Highly Cited
1979
Highly Cited
1979
Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid.
G. Peck
,
T. Olsen
,
+5 authors
J. Arnaud-Battandier
New England Journal of Medicine
1979
Corpus ID: 10339538
Fourteen patients with treatment-resistant cystic and conglobate acne were treated for four months with oral 13-cis-retinoic acid…
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Highly Cited
1972
Highly Cited
1972
Prophylaxis of chemically induced benign and malignant epithelial tumors by vitamin A acid (retinoic acid).
Werner Bollag
European Journal of Cancer
1972
Corpus ID: 46599332
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