Poloxamer

Known as: Poloxamer [Chemical/Ingredient], alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer 
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different… (More)
National Institutes of Health

Papers overview

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2011
2011
Fungal keratitis is a serious disease that can lead to loss of vision. Unfortunately, current therapeutic options often result in… (More)
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2010
Highly Cited
2010
The aim of the present work was to obtain an ophthalmic delivery system with improved mechanical and mucoadhesive properties that… (More)
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2008
2008
The influence of hyaluronic acid (HA) on the gelation properties of poloxamers blends has been studied with the aim of… (More)
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2007
Highly Cited
2007
Role of various water-soluble carriers was studied for dissolution enhancement of a poorly soluble model drug, rofecoxib, using… (More)
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2007
2007
Conventional ophthalmic solutions often eliminate rapidly after administration and cannot provide and maintain an adequate… (More)
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2005
Highly Cited
2005
In this work, we show that alteration of P407 gel content can affect drug release rates. The inorganic salts and PEG 400 commonly… (More)
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2005
2005
The aqueous solution of poly(ethylene glycol)-poly(caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG) triblock copolymers (> 15… (More)
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2001
Highly Cited
2001
Liquid suppository systems composed of poloxamers and bioadhesive polymers were easy to administer to the anus and mucoadhesive… (More)
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1999
1999
The surface chemical characterisation of sub-200 nm poly(DL-lactide co-glycolide) nanospheres has been carried out using the… (More)
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1998
Highly Cited
1998
The contact time of a vehicle on the cornea is of utmost importance for ocular drug delivery. In the present study rheological… (More)
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