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Point accepted mutation

Known as: PAM, Pam matrix 
A point accepted mutation — also known as a PAM — is the replacement of a single amino acid in the primary structure of a protein with another single… Expand
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Papers overview

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Highly Cited
2014
Highly Cited
2014
Background—Plasma triglyceride levels are heritable and are correlated with the risk of coronary heart disease. Sequencing of the… Expand
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Highly Cited
2013
Highly Cited
2013
The evolutionary significance of introgression has been discussed for decades. Questions about potential impacts of transgene… Expand
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Highly Cited
2009
Highly Cited
2009
Mutation accumulation (MA) experiments, in which mutations are allowed to drift to fixation in inbred lines, have been a… Expand
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Highly Cited
2008
Highly Cited
2008
A support stand assembly primarily designed for the adjustable support and positioning of work articles such as macrame, woven… Expand
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Highly Cited
2007
Highly Cited
2007
Anionic polyacrylamide (PAM) has been sold since 1995 to reduce irrigation‐induced erosion and enhance infiltration. Its soil… Expand
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Highly Cited
2004
Highly Cited
2004
During the past seventy years, worldwide more than 2250 varieties have been released that have been derived either as direct… Expand
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Highly Cited
2004
Highly Cited
2004
The use of ionizing radiation, such as X-rays, gamma rays and neutrons and chemical mutagens for inducing variation, is well… Expand
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Highly Cited
1997
Highly Cited
1997
Nature Genetics 15, 30–35 (1997). The name of the gene TBX5 was unintentionally left out of the title of this report. We regret… Expand
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Highly Cited
1996
Highly Cited
1996
To determine whether the presenilin 1 (PS1), presenilin 2 (PS2) and amyloid β-protein precursor (APP) mutations linked to… Expand
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Highly Cited
1995
Highly Cited
1995
The multirecombinant (/, ) evolution strategy (ES) is investigated for real-valued, N-dimensional parameter spaces. The analysis… Expand
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