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Point accepted mutation

Known as: PAM, Pam matrix 
A point accepted mutation — also known as a PAM — is the replacement of a single amino acid in the primary structure of a protein with another single… 
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BLASTBLOSUMBioinformaticsMarkov chain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Activating Mutations of Nand Kras in Multiple Myeloma Show Different Clinical Associations : Analysis of the Eastern Cooperative Oncology Group Phase I 11 Trial
Mutations of members of the rasfamily are among the most common oncogene mutations found in multiple myeloma (MM). We have… 
2001
2001
Influence of TP 53 Gene Alterations and c-erbB2 Expression on the Response to Treatment with Doxorubicin in Locally Advanced Breast Cancer 1
TP53 status [mutations, immunostaining, and loss of heterozygosity (LOH)], expression of c-erbB-2, bcl-2, and histological… 
Review
2000
Review
2000
In search of γ-secretase: Presenilin at the cutting edge
The effort to solve Alzheimer's disease (AD) has led to a salutary intersection between the desire to prevent a major health… 
Highly Cited
1997
Highly Cited
1997
Induced mutations and molecular techniques for crop improvement
1997
1997
Erratim: Mutations in the hepatocyte nuclear factor-1α gene in MODY and early-onset NIDDM: Evidence for a mutational hotspot in exon 4 (Diabetes (1997) 46 (528-535))
Highly Cited
1988
Highly Cited
1988
Temporal and Spatial Regulation of Plant Genes
First attempts to isolate plant genes were for those genes that are abun dantly expressed in a particular plant organ at a… 
1988
1988
Localisation polymorphism of mdg-1, copia, I and P mobile elements in genomes of Drosophila melanogaster, from data of inbred lines
Using data from in situ hybridisation of the giant chromosomes from salivary glands, mdg-1, I, copia, and P mobile element… 
1978
1978
Reduction of N-methyl-N'-nitro-N-nitrosoguanidine- Induced Mutations by Cobalt Chloride in Escherichia Coli
Since the discovery of a potent mutagenic action of N-methyl-N'nitro-N-nitrosoguanidine (MNNG) (Mandell and Greenberg, 1961… 
Highly Cited
1951
Highly Cited
1951
Structure of the incompatibility gene
1934
1934
The Meiotic Divisions of Haploid, Diploid and Tetraploid Tomatoes with Special Reference to the Prophase
1. The tomato polyploid series, haploid, diploid, and tetraploid has been described with special reference to the prophase of… 
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