Point accepted mutation

Known as: Pam matrix 
A point accepted mutation — also known as a PAM — is the replacement of a single amino acid in the primary structure of a protein with another single… (More)
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Topic mentions per year

1990-2015
01219902015

Papers overview

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2015
2015
The protr package offers a unique and comprehensive toolkit for generating various numerical representation schemes of protein… (More)
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2010
2010
In protein sequence alignment, residue similarity is usually evaluated by substitution matrix, which scores all possible… (More)
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2009
2009
In this paper we denonstrate that the use of the system of 2-adic numbers provides a new insight to some problems of genetics, in… (More)
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2008
2008
Hemophilia B is caused by a deficit or decreased activity of factor IX. Mutation in factor IX is made up of a majority of amino… (More)
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2005
2005
Sequence alignment is the procedure of comparing two (pair-wise alignment) or more (multiple sequence alignment) sequences by… (More)
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2004
2004
MOTIVATION We address the question of whether there exists an effective evolutionary model of amino-acid substitution that forms… (More)
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2003
2003
Point Accepted Mutation (PAM) is the Markov model of amino acid replacements in proteins introduced by Dayhoff and her co-workers… (More)
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Highly Cited
2001
Highly Cited
2001
Sexual selection may facilitate speciation because it can cause rapid evolutionary diversification of male mating signals and… (More)
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Highly Cited
1991
Highly Cited
1991
Scoring matrices for nucleic acid sequence comparison that are based on models appropriate to the analysis of molecular… (More)
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1990
1990
We have increased the sensitivity of DNA and protein sequence database searches by allowing similar but non-identical amino acids… (More)
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