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Plicamycin

Known as: MTH, Mithramycine, Plicamycinum 
An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the… 
National Institutes of Health

Related topics

Related topics

31 relations

Broader (5)

Antibiotics, AntineoplasticFluorescent DyesGlycosidesNucleic Acid Synthesis Inhibitors
Blood Coagulation DisordersHemorrhagic DisordersHypercalcemiaHypocalcemia

Narrower (9)

Mithracinechromomycin A2demycarosyl-3D-digitoxosylmithramycin SKdurhamycin A

Papers overview

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Highly Cited
2007
Highly Cited
2007
Effects of undersown crops on soil mineral N and grain yield of spring barley
Highly Cited
2002
Highly Cited
2002
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug…
Mithramycin is an aureolic acid-type antimicrobial and antitumor agent produced by Streptomyces argillaceus. Modifying post… 
Highly Cited
2001
Highly Cited
2001
Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry.
The interactions of self-complementary oligonucleotides with a group of metal-mediated DNA-binding drugs, including chromomycin A… 
Highly Cited
1993
Highly Cited
1993
Quantification of nuclear DNA and G-C content in marine macroalgae by flow cytometry of isolated nuclei
SummaryThe amounts of nuclear DNA in ten species of seaweeds belonging to the Rhodophyceae, Phaeophyceae, and Chlorophyceae were… 
Highly Cited
1989
Highly Cited
1989
Spectrofluorometry of dyes with DNAs of different base composition and conformation.
Highly Cited
1982
Highly Cited
1982
Trypanosoma cruzi: flow cytometric analysis. I. Analysis of total DNA/organism by means of mithramycin-induced fluorescence.
Total DNA/organism was determined by flow cytometry on stocks of 33 single-cell-isolate clones and one strain of mithramycin… 
Highly Cited
1976
Highly Cited
1976
Rapid staining methods for analysis of deoxyribonucleic acid and protein in mammalian cells.
Quantitative fluorescent staining and analysis of cellular deoxyribonucleic acid (DNA) were accomplished using three groups of… 
Highly Cited
1972
Highly Cited
1972
Advances in the gas chromatographic analysis of amino acid phenyl- and methylthiohydantoins.
Highly Cited
1970
Highly Cited
1970
Studies on the chemotherapy of experimental brain tumors: evaluation of 1,3-bis(2-chloroethyl)-l-nitrosourea, cyclophosphamide, mithramycin, and methotrexate.
Summary A brain tumor model has been utilized to test 4 chemotherapeutic agents. The model consists of C57BL male mice implanted… 
Highly Cited
1966
Highly Cited
1966
Physicochemical properties of complexes between deoxyribonucleic acid and antibiotics which affect ribonucleic acid synthesis (actinomycin, daunomycin, cinerubin, nogalamycin, chormomycin…
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