Plicamycin

Known as: MTH, Mithramycine, Plicamycinum 
An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the… (More)

Topic mentions per year

Topic mentions per year

1952-2017
020406019522016

Papers overview

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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Mild therapeutic hypothermia (MTH) has been integrated into international resuscitation guidelines. In the majority of… (More)
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Highly Cited
2006
Highly Cited
2006
Chromatin remodeling and transcription regulation are tightly controlled under physiological conditions. It has been suggested… (More)
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Highly Cited
2000
Highly Cited
2000
 The purpose of this study was to investigate the time course of skeletal muscle adaptations resulting from high-intensity, upper… (More)
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Highly Cited
1996
Highly Cited
1996
The expression of vascular endothelial growth factor (VEGF) has been implicated in brain tumor angiogenesis, and the promoter… (More)
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Highly Cited
1991
Highly Cited
1991
The promoter of the human dihydrofolate reductase (DHFR) gene contains two consensus binding sites for the DNA binding protein… (More)
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Highly Cited
1983
Highly Cited
1983
Mechanical chopping of plant tissues in the presence of mithramycin released intact nuclei representative of the cells within the… (More)
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Highly Cited
1983
Highly Cited
1983
A method has been developed that allows flow cytometry to be used for measuring the cellular DNA content of paraffin-embedded… (More)
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Highly Cited
1983
Highly Cited
1983
We have studied the effects of tamoxifen on the cell cycle kinetics of the endocrine-responsive MCF-7 human breast cancer cells… (More)
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Highly Cited
1976
Highly Cited
1976
Two DNA binding guanine-specific antibiotics, chromomycin A3 (CMA) and the closely related mithramycin (MM), were used as… (More)
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Highly Cited
1966
Highly Cited
1966
The nature and content of lytic bodies and the localization of acid phosphatase (AcPase) activity were investigated in… (More)
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