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Plevitrexed

Known as: (alphaS)-alpha-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid, Vamidex, Vamydex 
An orally bioavailable, small molecule, non-polyglutamatable, antifolate quinazoline derivative thymidine synthetase inhibitor with potential… 
National Institutes of Health

Related topics

Related topics

2 relations
ZD 9331topotecan/ZD9331

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Plevitrexed active in advanced gastric cancer
  • 2007
  • Corpus ID: 195105194
2005
2005
Novel Tumor-Selective Thymidylate Synthase Inhibitor Targeted to A-Folate Receptor – Overexpressing Tumors
BGC 945 is a cyclopenta[g]quinazoline–based, thymidylate synthase inhibitor specifically transported into A-folate receptor (A-FR… 
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