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Pimozide

Known as: 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-, Pimozidum, Pimozide [Chemical/Ingredient] 
A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Summary Background Schizophrenia is one of the most common, burdensome, and costly psychiatric disorders in adults worldwide… Expand
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Review
2019
Review
2019
Objective To systematically evaluate the efficacy of treatments for tics and the risks associated with their use. Methods This… Expand
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Highly Cited
2011
Highly Cited
2011
The transcription factor STAT5 is an essential mediator of the pathogenesis of chronic myelogenous leukemia (CML). In CML, the… Expand
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Review
2002
Review
2002
  • P. Seeman
  • Canadian journal of psychiatry. Revue canadienne…
  • 2002
  • Corpus ID: 14930109
Background: Al though the prin ci pal brain tar get that all an tipsy chotic drugs at tach to is the do pamine D2 re cep tor, tra… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The treatment of Tourette's disorder with classical neuroleptics is limited by their side effects. Risperidone is a… Expand
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE The authors evaluated the relative efficacy and safety of pimozide and haloperidol in the treatment of Gilles de la… Expand
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Highly Cited
1989
Highly Cited
1989
The results of this controlled study of the treatment of 57 patients with Gilles de la Tourette's syndrome suggested that both… Expand
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Highly Cited
1978
Highly Cited
1978
The dopamine receptor blocker pimozide attenuated lever-pressing and running for food reward in hungry rats. In each case the… Expand
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Highly Cited
1975
Highly Cited
1975
Low and high doses of a dopamine blocking agent had effects on lever pressing for intravenous amphetamine reward which resembled… Expand
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Highly Cited
1970
Highly Cited
1970
Abstract Fifteen neuroleptics of the phenothiazine, thioxanthene, dibenzazepine, butyrophenone or diphenylbutylamine type were… Expand
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