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Pimozide

Known as: 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-, Pimozidum, Pimozide [Chemical/Ingredient] 
A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic… 
National Institutes of Health

Related topics

Related topics

48 relations
24 HR Clarithromycin 500 MG Extended Release Oral TabletAzithromycinAzithromycin 500 MG InjectionAzithromycin 500 MG Oral Tablet

Narrower (4)

AntalonOpiranOrapR-6238

Broader (4)

Antipsychotic AgentsBenzimidazolesDopamine AntagonistsTranquilizing Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
A fatality involving moclobemide, sertraline, and pimozide.
A case is described involving a suspected fatal interaction between moclobemide and sertraline, in combination with the use of… 
1985
1985
Synthesis and release of luteinizing hormone in vitro by rat anterior pituitary cells: effects of gallopamil hydrochloride (D600) and pimozide.
We compared the role of Ca2+ in regulating GnRH-induced LH synthesis and release from cultured rat pituitary cells. LH synthesis… 
Highly Cited
1982
Highly Cited
1982
Psychological effects of buspirone.
Chief among the drawbacks of the benzodiazepines is the risk of a withdrawal syndrome when the drugs are discontinued after… 
1982
1982
Onychotillomania treated with pimozide (Orap).
A case of onychotillomania in a 70-year-old woman is presented. The disease had persisted for 51/2 years. All her fingernails… 
Highly Cited
1981
Highly Cited
1981
Adrenergic and dopaminergic modulation of growth hormone and prolactin secretion in normal and tumor bearing human pituitaries in monolayer culture.
Adrenergic and dopaminergic agonists administered in vivo stimulate GH secretion and inhibit PRL release. To investigate the… 
1978
1978
The social outcome of patients in a trial of long-term continuation therapy in schizophrenia: pimozide vs. fluphenazine
SYNOPSIS A blind social assessment at home was carried out twice during a year's follow-up of 41 patients on continuation therapy… 
Highly Cited
1978
Highly Cited
1978
Lisuride hydrogen maleate: evidence for a long lasting dopaminergic activity in humans.
In 12 acromegalics a single oral dose of 0.2 mg lisuride, an ergoline derivative, significantly reduced plasma PRL but not GH… 
1976
1976
Effect of the dopamine receptor blocking agent pimozide on the growth hormone response to arginine and exercise and on the spontaneous growth hormone fluctuations.
Pimozide, a specific blocker of dopamine receptors, was administered orally to 10 diabetics for 2 days before an arginine… 
1976
1976
Histochemical changes in the blood cells of schizophrenic patients under pimozide treatment.
Chromatin structure and nucleohistone pattern were investigated histochemically in the neutrophils of 11 schizophrenics and 16… 
1976
1976
Inhibition of mid-cycle gonadotrophin release in healthy women by pimozide and fusaric acid.
The effects of pimozide, a drug blocking dopamine receptors, and fusaric acid, an inhibitor of dopamine beta-hydroxylase, on mid… 
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