Pimozide

Known as: 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-, Pimozidum, Pimozide [Chemical/Ingredient] 
A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The transcription factor STAT5 is an essential mediator of the pathogenesis of chronic myelogenous leukemia (CML). In CML, the… (More)
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Highly Cited
2011
Highly Cited
2011
Opioid system dysregulation has been observed in both genetic and high-fat diet (HFD)-induced models of obesity. An understanding… (More)
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Highly Cited
1997
Highly Cited
1997
Several "taste reactivity" studies of dopamine and reward have concluded that pimozide suppresses the hedonic reaction patterns… (More)
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Highly Cited
1997
Highly Cited
1997
Studies with laboratory animals have shown that dopamine antagonists block the rewarding and interoceptive effects of amphetamine… (More)
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Highly Cited
1989
Highly Cited
1989
The results of this controlled study of the treatment of 57 patients with Gilles de la Tourette's syndrome suggested that both… (More)
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1989
1989
Pimozide was compared with carbamazepine in a double-blind crossover trial in 48 patients with trigeminal neuralgia who were… (More)
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Highly Cited
1987
Highly Cited
1987
The involvement of dopaminergic systems in appetitive and ingestive feeding behaviors was investigated in two experiments… (More)
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Highly Cited
1983
Highly Cited
1983
Animals with a history of receiving daily injections of +-amphetamine in a specific environment showed a placebo effect (enhanced… (More)
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Highly Cited
1978
Highly Cited
1978
The dopamine receptor blocker pimozide attenuated lever-pressing and running for food reward in hungry rats. In each case the… (More)
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Highly Cited
1975
Highly Cited
1975
Low and high doses of a dopamine blocking agent had effects on lever pressing for intravenous amphetamine reward which resembled… (More)
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