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Phytanic Acid

Known as: Hexadecanoic acid, 3,7,11,15-tetramethyl-, Acid, Phytanic, acid phytanic 
A 20-carbon branched chain fatty acid. In phytanic acid storage disease (REFSUM DISEASE) this lipid may comprise as much as 30% of the total fatty… 
National Institutes of Health

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12 relations

Narrower (5)

2-hydroxyphytanic acid2-oxophytanic acidPhytanatephytanoyl-coenzyme A
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes.
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched-chain fatty acid which, due to the methyl-group at the 3… 
1994
1994
2-Hydroxyphytanic acid oxidase activity in rat and human liver and its deficiency in the Zellweger syndrome.
Highly Cited
1985
Highly Cited
1985
Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: Plasma changes and skin fibroblast phytanic acid oxidase
SummaryCerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease patients can be divided into at… 
Highly Cited
1984
Highly Cited
1984
Infantile Refsum's disease (phytanic acid storage disease): a variant of Zellweger's syndrome?
The activity of phytanic acid oxidase is low in infantile and adult Refsum's disease, and in the cerebro‐hepato‐renal (Zellweger… 
Highly Cited
1984
Highly Cited
1984
Patterns of Refsum's disease. Phytanic acid oxidase deficiency.
Four children each exhibiting a profound deficiency of phytanic acid oxidase activity in cultured skin fibroblasts but with very… 
1983
1983
Phytanic acid storage disease
Heredopathia atactica polyneuritiformis is a biochemically defined disease with a specific dietary treatment. It is an autosomal… 
Highly Cited
1969
Highly Cited
1969
Refsum's disease: defective oxidation of phytanic acid in tissue cultures derived from homozygotes and heterozygotes.
Abstract A defect in phytanic acid oxidation was demonstrated in cultured fibroblasts derived from skin biopsies of 11 patients… 
Highly Cited
1967
Highly Cited
1967
A generalized disorder of nervous system, skeletal muscle and heart resembling Refsum's disease and Hurler's syndrome. I. Clinical, pathologic and biochemical characteristics.
Highly Cited
1966
Highly Cited
1966
Phytol metabolism in the bovine.
1964
1964
Blood lipids. 4. The isolation of 3,7,11,15-tetramethylhexadecanoic acid (phytanic acid) from ox-plasma lipids.
The presence of an unusual peak on gas-liquid chromatograms of methyl esters of fatty acids derived from lipids 
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