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Phosphoribosylaminoimidazolecarboxamide Formyltransferase

Known as: Ribonucleotide Transformylase, Aminoimidazolecarboxamide, Transformylase, AICAR, Formyltransferase, AICAR 
An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The measurement of an excess in the cosmic-ray electron spectrum between 300 and 800 GeV by the ATIC experiment has - together… Expand
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Highly Cited
2008
Highly Cited
2008
PAMELA and ATIC recently reported excesses in e± cosmic rays. Since the interpretation in terms of DM annihilations was found to… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Methotrexate (MTX) is an antifolate agent that is often associated with toxicity. This study investigated whether risk… Expand
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Highly Cited
2000
Highly Cited
2000
The subset of CD30-positive anaplastic large cell lymphomas (ALCL) with the NPM-ALK gene fusion arising from the t(2;5)(p23;q35… Expand
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Highly Cited
2000
Highly Cited
2000
Anaplastic lymphoma kinase (ALK)-positive lymphomas ("ALKomas") constitute a distinct molecular and clinicopathological entity… Expand
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Highly Cited
2000
Highly Cited
2000
The non-Hodgkin lymphoma (NHL) subtype anaplastic large-cell lymphoma (ALCL) is frequently associated with a t(2;5)(p23;q35) that… Expand
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Highly Cited
1991
Highly Cited
1991
We have investigated the structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate (DDATHF) that determine the activity of… Expand
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Highly Cited
1987
Highly Cited
1987
We have investigated the role of dihydrofolate (H2PteGlu) accumulation in the inhibition of de novo purine synthesis by… Expand
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Highly Cited
1986
Highly Cited
1986
With the use of a continuous spectrophotometric assay and initial rates determined by the method of Waley [Biochem. J. (1981) 193… Expand
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Highly Cited
1985
Highly Cited
1985
We report the enhanced inhibitory potency of methotrexate (MTX) polyglutamates and dihydrofolate pentaglutamate on the catalytic… Expand
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