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Phosphoribosylamine-glycine ligase

Known as: glycinamide ribonucleotide synthetase, phosphoribosyl-glycineamide synthetase, phosphoribosylglycinamide synthetase 
National Institutes of Health

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4 relations

Broader (1)

Carbon-Nitrogen Ligases
GART geneGART wt Allelephosphoribosylamine-glycine ligase activity

Papers overview

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2006
2006
Channeling in purine biosynthesis : efforts to detect interactions between PurF and PurD and characterization of the FGAR-AT complex
Purine biosynthesis has been used as a paradigm for the study of metabolism of unstable molecules. Both phosphoribosylamine (PRA… 
2004
2004
Assignment of human phosphoribosylglycinamide synthetase locus to region 21q221
SummaryThe enzymatic activity of phosphoribosylglycinamide synthetase (GARS) has been studied in several cases of partial… 
Review
2004
Review
2004
GART, SON, IFNAR, and CRF2-4 genes cluster on human Chromosome 21 and mouse Chromosome 16
Down syndrome is caused by trisomy 21 (Lejeune et al. 1959), a common chromosomal abnormality observed in newborn children and a… 
2000
2000
Temperature-Dependent Function of the Glutamine Phosphoribosylpyrophosphate Amidotransferase Ammonia Channel and Coupling with Glycinamide Ribonucleotide Synthetase in a Hyperthermophile
ABSTRACT Genes encoding glutamine phosphoribosylpyrophosphate amidotransferase (GPAT) and glycinamide ribonucleotide synthetase… 
1994
1994
Development of a mouse model for the study of human purine metabolism.
Patients with Down syndrome are known to be hyperuricemic and this condition is thought to result from the over-production of… 
1965
1965
PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE OF AEROBACTER AEROGENES. PURIFICATION AND PROPERTIES, AND NONENZYMATIC FORMATION OF ITS SUBSTRATE 5'-PHOSPHORIBOSYLAMINE.
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