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Phosphoribosyl Pyrophosphate

Known as: Phosphoribosyl Pyrophosphate [Chemical/Ingredient], Pyrophosphate, Phosphoribosyl, alpha-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) 
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
National Institutes of Health

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In BloodProcess of secretionagonistsanalogs & derivatives

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2006
2006
Expression, purification, crystallization and preliminary X-ray diffraction analysis of human phosphoribosyl pyrophosphate synthetase 1 (PRS1).
Phosphoribosyl pyrophosphate synthetase (PRS; EC 2.7.6.1) catalyzes the reaction of ribose-5-phosphate (R5P) with ATP to yield… 
1986
1986
Phosphoribosyl pyrophosphate and phosphoribosyl pyrophosphate synthetase in rat mammary gland. Changes in the lactation cycle and effects of diabetes, insulin and phenazine methosulphate.
Changes in the tissue content of phosphoribosyl pyrophosphate (PPRibP), glucose 6-phosphate, ribose 5-phosphate (Rib5P), RNA and… 
1984
1984
Metabolism of hypoxanthine in isolated rat hepatocytes.
The hepatic metabolism of hypoxanthine was investigated by studying both the fate of labelled hypoxanthine, added at micromolar… 
1981
1981
Synthetic nucleosides and nucleotides. XVIII. Synthesis and cytostatic activity of 5-fluoropyrimidine nucleosides of 3-amino-3-deoxy-beta-D-ribofuranose and related compounds.
Treatment of 1, 2 : 5, 6-di-O-isopropylidene-3-amino-3-deoxy-α-D-allofuranose (1) with trifluoroacetic anhydride afforded… 
1978
1978
In vitro and in vivo age-related modification of human erythrocyte phosphoribosyl pyrophosphate synthetase.
Upon storage, human erythrocyte phosphoribosyl pyrophosphate synthetase (PRibPP synthetase, EC 2.7.6.1) from normal individuals… 
1978
1978
Synthetic nucleosides and nucleotides. XI. Facile synthesis and antitumor activities of various 5-fluoropyrimidine nucleosides.
Condensation of 2, 4-bis-trimethylsilyloxy-5-fluoropyrimidine (2a) with 1-O-acetyl-2, 3, 5-tri-O-benzoyl-β-D-ribofuranose (3a) by… 
1977
1977
2-C-nitromethyl and 2-C-aminomethyl derivatives of D-ribose. Preparation of 2'-C-nitromethyluridines.
Syntheses of derivatives of 2-C-nitromethyl-D-ribofuranose from a 3-C-nitromethyl-D-allofuranose are reported. The use of two of… 
1976
1976
Potentiation by guanine nucleosides of the growth-inhibitory effects of adenosine analogs on L1210 and sarcoma 180 cells in culture.
The growth-inhibitory effect of 6-methylmercaptopurine riboside (MMPR) against leukemia L1210 cells in culture was dramatically… 
1975
1975
Effects of hormones and drugs on phosphoribosyl pyrophosphate concentrations in mouse liver.
Concentrations of phosphoribosyl pyrophosphate (PP-ribose-P) in mouse liver were studied as a function of time of day and… 
1974
1974
Inhibition of purine ribonucleotide and phosphoribosyl pyrophosphate synthesis by 6-cyclopentylthio-9-hydroxymethylpurine and structurally related compounds.
Summary 6-Cyclopentylthio-9-hydroxymethylpurine, 9-(3-aminopropyl)adenine, and structurally related compounds inhibited the…