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Phosphoribosyl Pyrophosphate

Known as: Phosphoribosyl Pyrophosphate [Chemical/Ingredient], Pyrophosphate, Phosphoribosyl, alpha-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) 
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
To identify C-MYC targets rate-limiting for proliferation of malignant melanoma, we stably inhibited C-MYC in several human… Expand
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Highly Cited
2007
Highly Cited
2007
Primary transcripts of certain microRNA (miRNA) genes are subject to RNA editing that converts adenosine to inosine. However, the… Expand
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Highly Cited
2007
Highly Cited
2007
We have identified missense mutations at conserved amino acids in the PRPS1 gene on Xq22.3 in two families with a syndromic form… Expand
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2004
2004
Using a transgene-based screening, we previously isolated several Arabidopsis mutants defective in protein import into… Expand
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Highly Cited
2002
Highly Cited
2002
We report the synthesis of 1'-deoxy-1'-(benzimidazol-1-yl)-beta-D-ribofuranose 7 and 1'-deoxy-1'-phenyl-beta-D-ribofuranose 2… Expand
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Highly Cited
2000
Highly Cited
2000
The structure of the viscous extracellular polysaccharide (glycan) of desiccation-tolerant Nostoc commune DRH-1 was determined… Expand
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Highly Cited
2000
Highly Cited
2000
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. The rate-limiting step in this… Expand
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1988
1988
  • G. Yeh, J. Phang
  • The Journal of biological chemistry
  • 1988
  • Corpus ID: 12084634
Recent studies have shown that pyrroline 5-carboxylate, the intermediate in the interconversions of proline, ornithine, and… Expand
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Highly Cited
1982
Highly Cited
1982
Plasmodium falciparum trophozoites were isolated by mechanical rupture of infected human erythrocytes followed by a series of… Expand
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1953
1953
WE have formulated a structure for the nucleic acids which is compatible with the main features of the X-ray diagram and with the… Expand
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