Phosphoribosyl Pyrophosphate

Known as: Phosphoribosyl Pyrophosphate [Chemical/Ingredient], Pyrophosphate, Phosphoribosyl, alpha-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) 
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
National Institutes of Health

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In BloodProcess of secretionagonistsanalogs & derivatives
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2013
2013
Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate.
Cells must increase synthesis of purine nucleotides/deoxynucleotides before or during S-phase. We found that rates of purine… (More)
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2013
2013
Anthranilate phosphoribosyl transferase (TrpD) generates phosphoribosylamine for thiamine synthesis from enamines and phosphoribosyl pyrophosphate.
Anthranilate phosphoribosyl transferase (TrpD) has been well characterized for its role in the tryptophan biosynthetic pathway… (More)
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Highly Cited
2007
Highly Cited
2007
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs.
Primary transcripts of certain microRNA (miRNA) genes are subject to RNA editing that converts adenosine to inosine. However, the… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic…
We have identified missense mutations at conserved amino acids in the PRPS1 gene on Xq22.3 in two families with a syndromic form… (More)
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2004
2004
Characterization of Arabidopsis glutamine phosphoribosyl pyrophosphate amidotransferase-deficient mutants.
Using a transgene-based screening, we previously isolated several Arabidopsis mutants defective in protein import into… (More)
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2001
2001
Stimulation of Phosphoribosyl Pyrophosphate and Purine Nucleotide Production by Pyrroline 5-Carboxylate in Human Erythrocytes *
  • Grace Chao YehS, James M. Phangg
  • 2001
Recent studies have shown that pyrroline 5-carboxylate, the intermediate in the interconversions of proline, ornithine, and… (More)
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1998
1998
Identification of a sodium chloride-regulated promoter in Lactococcus lactis by single-copy chromosomal fusion with a reporter gene
 An integration vector, pORI13, was developed to screen in Lactococcus lactis for expression signals induced by changes in the… (More)
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1989
1989
Phosphoribosyl pyrophosphate and the measurement on inorganic pyrophosphate in plant tissues
This work provides further evidence that plants contain appreciable amounts of inorganic pyrophosphate (PPi), and that breakdown… (More)
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1984
1984
A spectrophotometric assay of phosphoribosyl pyrophosphate synthetase.
A simple spectrophotometric assay of phosphoribosyl pyrophosphate synthetase from human erythrocytes is described. The kinetic… (More)
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1974
1974
Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver.
Phosphoribosyl pyrophosphate synthetase has been purified extensively from rat liver. Gel filtration studies indicate that the… (More)
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