FAQ

Phospholipase A2 Inhibitors

Known as: A2 Antagonists, Phospholipase, Phospholipase A2 Antagonists, Antagonists, Phospholipase A2 
Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2016
01219822016

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11 relations

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AX 059PF-5212372darapladibecopladib
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In Bloodchemical synthesisisolation & purification analysisstandards characteristics

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Phospholipase A2 Inhibitors
In Blood
chemical synthesis
standards characteristics
darapladib
pyrrophenone

Papers overview

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2016
2016
rBaltMIP, a recombinant alpha-type myotoxin inhibitor from Bothrops alternatus (Rhinocerophis alternatus) snake, as a potential candidate to complement the antivenom therapy.
Phospholipase A2 inhibitors (PLIs) are important targets in the search and development of new drugs. This study aimed at… (More)
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Review
1999
Review
1999
Regulation of platelet-activating factor (PAF) activity in human diseases by phospholipase A2 inhibitors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengers.
  • Philip V Peplow
  • Prostaglandins, leukotrienes, and essential fatty…
  • 1999
The aim of this review is to present recent findings indicating the likely involvement of platelet-activating factor (PAF) in… (More)
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1990
1990
Effect of phospholipase A2 inhibitors on mouse T lymphocytes. II. Phospholipase A2 inhibitors induce T cell hybridomas and a T cell clone for the formation of glycosylation-inhibiting factor.
The mouse T cell hybridoma 12H5 cells constitutively form glycosylation-enhancing factor (GEF) and produce both IgE-potentiating… (More)
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Review
1990
Review
1990
Macrophage phospholipase A2 activity and eicosanoid production: studies with phospholipase A2 inhibitors in P388D1 cells.
 
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1989
1989
Superoxide generation is inhibited by phospholipase A2 inhibitors. Role for phospholipase A2 in the activation of the NADPH oxidase.
The stimulation of O2.- generation by phorbol 12-myristate 13-acetate (PMA) in human neutrophil-derived cytoplasts was inhibited… (More)
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1989
1989
Effect of phospholipase A2 inhibitors on mouse T lymphocytes. I. Phospholipase A2 inhibitors exert similar immunological activities as glycosylation inhibiting factor.
Since our previous experiments suggested that glycosylation-inhibiting factor (GIF) is a phosphorylated derivative of a… (More)
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1982
1982
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity by phospholipase A2 inhibitors and lipoxygenase inhibitor.
Application of 12-O-tetradecanoylphorbol-13-acetate (TPA; 20 nmol/mouse), a tumor-promoting agent, to mouse skin results in an… (More)
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