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Phospholipase A2 Inhibitors
Known as:
A2 Antagonists, Phospholipase
, Phospholipase A2 Antagonists
, Antagonists, Phospholipase A2
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Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme.
National Institutes of Health
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Related topics
Related topics
11 relations
Narrower (7)
AX 059
PF-5212372
darapladib
ecopladib
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In Blood
aspects of radiation effects
chemical synthesis
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Up-regulation of the expressions of phospholipase A2 inhibitors in the liver of a venomous snake by its own venom phospholipase A2.
Kohshi Kinkawa
,
R. Shirai
,
+4 authors
S. Inoue
Biochemical and Biophysical Research…
2010
Corpus ID: 8095937
2005
2005
Secretory phospholipase A2 inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2
W. Hope
,
Ting Chen
,
D. Morgan
Agents and Actions
2005
Corpus ID: 39209217
Human cytosolic phospholipase A2 (cPLA2, 85 kDa) appears to be pharmacologically distinct from human secretory phospholipase A2…
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1998
1998
The therapeutic potential for phospholipase A2 inhibitors
R. Mayer
,
L. Marshall
1998
Corpus ID: 74267036
Modulation of pro-inflammatory lipid mediator production by inhibition of phospholipase A2 (PLA2) activity remains a potential…
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Review
1995
Review
1995
Secretory phospholipase A2 inhibitors. Possible new anti-inflammatory agents.
K. Tanaka
,
H. Arita
Agents and actions. Supplements
1995
Corpus ID: 23932404
Secretory phospholipase A2 (sPLA2) is now clearly considered to be involved in the pathogenesis of both experimental and clinical…
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1994
1994
Rational modification of human synovial fluid phospholipase A2 inhibitors.
Pisabarro Mt
,
A. Ortiz
,
+6 authors
G. Carganico
Journal of Medicinal Chemistry
1994
Corpus ID: 36634837
Mammalian nonpancreatic secretory phospholipase A2 (PLAz) splits the 2-acyl bond in 1,2-diacylpho~phatide.~ This enzyme has been…
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Highly Cited
1994
Highly Cited
1994
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis.
M. Locati
,
Dan Zhou
,
W. Luini
,
Virgilio Evangelista
,
Alberto Mantovani
,
Silvano Sozzani
Journal of Biological Chemistry
1994
Corpus ID: 43316196
1993
1993
Prostaglandin F2 alpha synthesis in the hippocampal mossy fiber synaptosomal preparation: I. Dependence in arachidonic acid, phospholipase A2, calcium availability and membrane depolarization.
D. Separovic
,
R. Dorman
Prostaglandins, Leukotrienes and Essential Fatty…
1993
Corpus ID: 33822336
1991
1991
Group II phospholipase A2 inhibitors suppressed lysophosphatidylserine-dependent degranulation of rat peritoneal mast cells.
M. Murakami
,
I. Kudo
,
Y. Fujimori
,
H. Suga
,
K. Inoue
Biochemical and Biophysical Research…
1991
Corpus ID: 20930328
1984
1984
Inhibition of lipid peroxidation in muscle homogenates by phospholipase A2 inhibitors
M. Jackson
,
D. Jones
,
E. J. Harris
Bioscience Reports
1984
Corpus ID: 13138559
Chlorpromazine, mepacrine, tetracaine, dibucaine, chloroquine, and procaine have been shown to inhibit the iron- and ascorbate…
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Highly Cited
1979
Highly Cited
1979
Anti‐inflammatory and platelet anti‐aggregant activity of phospholipase‐A2 inhibitors
E. Vallée
,
J. Gougat
,
J. Navarro
,
J. F. DELAHAYES
The Journal of pharmacy and pharmacology
1979
Corpus ID: 30222172
Mepacrine, papaverine, p‐bromophenacyl bromide and 2,3‐dibromo(4′‐cyclohexyl‐3′‐chloro)‐phenyl‐4‐oxo‐butyric acid (CB 874…
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