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Phospholipase A2 Inhibitors

Known as: A2 Antagonists, Phospholipase, Phospholipase A2 Antagonists, Antagonists, Phospholipase A2 
Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme.
National Institutes of Health

Papers overview

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2010
2010
BackgroundAn early event in the neuropathology of prion and Alzheimer's diseases is the loss of synapses and a corresponding… Expand
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2010
2010
Venomous snakes such as Gloydius brevicaudus have three distinct types of phospholipase A(2) inhibitors (PLIalpha, PLIbeta, and… Expand
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2009
2009
Phase II results of the trials of two phospholipase A2 inhibitors which may be of value in the treatment of atherosclerosis and… Expand
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2006
2006
Mammalian secreted phospholipases A(2) (sPLA(2)s) constitute a family of structurally related enzymes that are likely to play… Expand
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2005
2005
Human cytosolic phospholipase A2 (cPLA2, 85 kDa) appears to be pharmacologically distinct from human secretory phospholipase A2… Expand
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2004
2004
A key feature of prion diseases is the conversion of the cellular prion protein (PrPC) into disease-related isoforms (PrPSc), the… Expand
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1999
1999
Tumour necrosis factor (TNF) is a key regulator of inflammation and immunity. The cellular effects exerted by TNF depend, apart… Expand
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1994
1994
Mammalian nonpancreatic secretory phospholipase A2 (PLAz) splits the 2-acyl bond in 1,2-diacylpho~phatide.~ This enzyme has been… Expand
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1991
1991
Rat peritoneal mast cells were sensitized with IgE and challenged with the specific antigen in the presence of… Expand
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1989
1989
The stimulation of O2.- generation by phorbol 12-myristate 13-acetate (PMA) in human neutrophil-derived cytoplasts was inhibited… Expand
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