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Phospholipase A2, human

Known as: EC 3.1.1.4, Phosphatidylcholine 2-Acylhydrolase 1B, Phospholipase A2 Group IB 
Phospholipase A2 (148 aa, ~16 kDa) is encoded by the human PLA2G1B gene. This protein plays a role in fatty acid metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2) are the two key enzymes in the metabolism of polyunsaturated fatty… Expand
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Highly Cited
2007
Highly Cited
2007
We investigated the role of phospholipase A2 (PLA2) and the effects of PLA2 products (polyunsaturated fatty acids and… Expand
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Review
2007
Review
2007
The deacylation-reacylation cycle is an important mechanism responsible for the introduction of polyunsaturated fatty acids into… Expand
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Highly Cited
2004
Highly Cited
2004
A health questionnaire based on parental observations of clinical signs of fatty acid deficiency (FAD) showed that patients with… Expand
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Highly Cited
2001
Highly Cited
2001
Phospholipase A2 (PLA2) hydrolyzes phospholipids to free fatty acids and lysolipids and thus initiates the biosynthesis of… Expand
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Highly Cited
1997
Highly Cited
1997
Secretory nonpancreatic type II phospholipase A2 (snpPLA2) hydrolyzes fatty acids at the sn-2 position in phospholipids releasing… Expand
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Highly Cited
1995
Highly Cited
1995
Intact human sperm incorporated radiolabelled fatty acids into membrane phospholipids when incubated in medium containing bovine… Expand
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Highly Cited
1991
Highly Cited
1991
Phospholipase A2 (PLA2) enzymes hydrolyze membrane phospholipids liberating fatty acid and lysophospholipid. This event is… Expand
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Highly Cited
1990
Highly Cited
1990
During oxidative modification of low density lipoprotein (LDL) there is extensive degradation of phosphatidylcholine (PtdCho) to… Expand
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Highly Cited
1981
Highly Cited
1981
The turnover of phospholipid fatty acid moieties of bone marrow-derived macrophages was analyzed by separate determination of… Expand
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