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Phospholipase A2, human

Known as: EC 3.1.1.4, Phosphatidylcholine 2-Acylhydrolase 1B, Phospholipase A2 Group IB 
Phospholipase A2 (148 aa, ~16 kDa) is encoded by the human PLA2G1B gene. This protein plays a role in fatty acid metabolism.
National Institutes of Health

Related topics

Related topics

21 relations
Arachidonic Acid Metabolism PathwayEnzyme GeneEsterase GeneExtracellular Space

Broader (1)

Group IB Phospholipases A2

Papers overview

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Highly Cited
2002
Highly Cited
2002
Spatio-temporal expression of patatin-like lipid acyl hydrolases and accumulation of jasmonates in elicitor-treated tobacco leaves are not affected by endogenous levels of salicylic acid.
We have previously isolated three tobacco genes (NtPat) encoding patatin-like proteins, getting rapidly induced during the… 
1998
1998
Direct imaging by cryo-TEM shows membrane break-up by phospholipase A2 enzymatic activity.
Phospholipid hydrolysis to free fatty acid and 1-lyso-phospholipid by water-soluble phospholipase A2 (PLA2) at the surface of… 
1998
1998
Biosynthesis of triacylglycerols containing ricinoleate in castor microsomes using 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine as the substrate of oleoyl-12-hydroxylase
We have examined the biosynthetic pathway of triacylglycerols containing ricinoleate to determine the steps in the pathway that… 
Highly Cited
1995
Highly Cited
1995
Phospholipase A2 controls the induction of short-term versus long-term depression in the cerebellar Purkinje neuron in culture
Highly Cited
1993
Highly Cited
1993
Potential role of phospholipase A2 in HL-60 cell differentiation to macrophages induced by protein kinase C activation.
2-Lysophosphatidylcholine and cis-unsaturated fatty acids such as linoleic and linolenic acids, which are the products of the… 
1990
1990
Phospholipase A2 and 3H-hemicholinium-3 binding sites in rat brain: a potential second-messenger role for fatty acids in the regulation of high-affinity choline uptake
The involvement of phospholipase A2 (PLA2) and fatty acid release in the regulation of sodium-dependent high-affinity choline… 
1985
1985
Hydrolysis of Endogenous Phospholipids by Rat Brain Microsomes
Phosphatidylcholine of rat brain microsomes was labeled in vivo by intracerebral injection of either [3H]oleic acid or [methyl‐3H… 
Highly Cited
1985
Highly Cited
1985
Inhibition of human platelet phospholipase A2 activity by unsaturated fatty acids.
Phospholipase A2 (PLA2; phosphatide 2-acylhydrolase, EC 3.1.1.4) activity from human platelets increases significantly when the… 
Highly Cited
1981
Highly Cited
1981
Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases.
1978
1978
Phospholipid-deacylating enzymes of rat stomach mucosa.
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