Phosphoglycerate Kinase 1

Known as: PRP 2, EC 2.7.2.3, PGK1 
Phosphoglycerate kinase 1 (417 aa, ~45 kDa) is encoded by the human PGK1 gene. This protein plays a role in glycolysis.

Topic mentions per year

Topic mentions per year

1971-2017
010203019712017

Papers overview

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2010
2010
Tumor and stromal interactions in the tumor microenvironment are critical for oncogenesis and cancer progression. Our… (More)
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2006
2006
Pancreatic ductal adenocarcinoma (PDAC) is a common malignancy with a very low 5-year survival rate. Currently, there are no… (More)
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Highly Cited
2004
Highly Cited
2004
Prediction of gene regulatory sequences using phylogenetic footprinting has advanced considerably but lacks experimental… (More)
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2002
2002
BACKGROUND Multidrug resistance is a significant barrier to the development of successful cancer treatment. To identify genetic… (More)
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1999
Highly Cited
1999
The mRNA surveillance system is known to rapidly degrade aberrant mRNAs that contain premature termination codons in a process… (More)
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1995
Highly Cited
1995
The first step in the decay of several yeast mRNAs is the shortening of the poly(A) tail, which for the MFA2 transcript triggers… (More)
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Highly Cited
1994
Highly Cited
1994
Hypoxia-inducible factor 1 (HIF-1) activates erythropoietin gene transcription in Hep3B cells subjected to hypoxia. HIF-1… (More)
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Highly Cited
1993
Highly Cited
1993
Nonsense mutations in a gene can accelerate the decay rate of the mRNA transcribed from that gene, a phenomenon we describe as… (More)
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Highly Cited
1991
Highly Cited
1991
mRNA decay rates often increase when translation is terminated prematurely due to a frameshift or nonsense mutation. We have… (More)
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Highly Cited
1990
Highly Cited
1990
We developed a procedure to measure mRNA decay rates in the yeast Saccharomyces cerevisiae and applied it to the determination of… (More)
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