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Gluconeogenesis
Known as:
Gluconeogenic Process
, glucose biosynthesis
, glucose biosynthetic process
The biosynthesis of new glucose as opposed to that generated by the metabolism of glycogen. Gluconeogenesis occurs mainly in the liver or kidneys…
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National Institutes of Health
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Related topics
Related topics
33 relations
ADIPOQ gene
ADIPOQ wt Allele
Alanine Aminotransferase 1, human
Alanine Aminotransferase 2, human
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Broader (2)
carbohydrate biosynthetic process
glucose metabolism
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
A. Koh
,
F. Vadder
,
P. Kovatcheva-Datchary
,
F. Bäckhed
Cell
2016
Corpus ID: 8562345
Highly Cited
2014
Highly Cited
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
A. Madiraju
,
D. Erion
,
+14 authors
G. Shulman
Nature
2014
Corpus ID: 4458896
Metformin is considered to be one of the most effective therapeutics for treating type 2 diabetes because it specifically reduces…
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Highly Cited
2010
Highly Cited
2010
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
M. Foretz
,
S. Hébrard
,
+6 authors
B. Viollet
Journal of Clinical Investigation
2010
Corpus ID: 14004271
Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein…
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Review
2005
Review
2005
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.
B. Kahn
,
T. Alquier
,
D. Carling
,
D. Hardie
Cell Metabolism
2005
Corpus ID: 38770643
Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
P. Puigserver
,
J. Rhee
,
+8 authors
B. Spiegelman
Nature
2003
Corpus ID: 4382480
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately…
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Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
P. Puigserver
,
J. Rhee
,
+8 authors
B. Spiegelman
Nature
2003
Corpus ID: 7970258
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately…
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Highly Cited
2001
Highly Cited
2001
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
J. C. Yoon
,
P. Puigserver
,
+9 authors
B. Spiegelman
Nature
2001
Corpus ID: 11184579
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the…
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Highly Cited
2001
Highly Cited
2001
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
S. Herzig
,
Fanxin Long
,
+9 authors
M. Montminy
Nature
2001
Corpus ID: 4412426
When mammals fast, glucose homeostasis is achieved by triggering expression of gluconeogenic genes in response to glucagon and…
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Review
1992
Review
1992
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis.
S. Pilkis
,
D. Granner
Annual Review of Physiology
1992
Corpus ID: 36066589
Understanding the regulation of hepatic glucose metabolism had its foundation in the elucidation of several pathways, but recent…
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Highly Cited
1970
Highly Cited
1970
Alanine: Key Role in Gluconeogenesis
P. Felig
,
Thomas Pozefsk
,
Errol Marlis
,
G. Cahill
Science
1970
Corpus ID: 45599760
Of 20 amino acids measured, alanine is the principal amino acid released by forearm muscle of man, in accord with its being the…
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