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Gluconeogenesis

Known as: Gluconeogenic Process, glucose biosynthesis, glucose biosynthetic process 
The biosynthesis of new glucose as opposed to that generated by the metabolism of glycogen. Gluconeogenesis occurs mainly in the liver or kidneys… Expand
National Institutes of Health

Related topics

Related topics

33 relations
ADIPOQ geneADIPOQ wt AlleleAlanine Aminotransferase 1, humanAlanine Aminotransferase 2, human
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Broader (2)

carbohydrate biosynthetic processglucose metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
A compelling set of links between the composition of the gut microbiota, the host diet, and host physiology has emerged. Do these… Expand
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Highly Cited
2014
Highly Cited
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
Metformin is considered to be one of the most effective therapeutics for treating type 2 diabetes because it specifically reduces… Expand
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Highly Cited
2010
Highly Cited
2010
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein… Expand
Review
2005
Review
2005
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular energy status, and recent data… Expand
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Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand
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Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand
Highly Cited
2001
Highly Cited
2001
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… Expand
Highly Cited
2001
Highly Cited
2001
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
When mammals fast, glucose homeostasis is achieved by triggering expression of gluconeogenic genes in response to glucagon and… Expand
Review
1992
Review
1992
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis.
Understanding the regulation of hepatic glucose metabolism had its foundation in the elucidation of several pathways, but recent… Expand
Highly Cited
1992
Highly Cited
1992
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.
UNLABELLED To quantitate hepatic glycogenolysis, liver glycogen concentration was measured with 13C nuclear magnetic resonance… Expand
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