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Gluconeogenesis

Known as: Gluconeogenic Process, glucose biosynthesis, glucose biosynthetic process 
The biosynthesis of new glucose as opposed to that generated by the metabolism of glycogen. Gluconeogenesis occurs mainly in the liver or kidneys… Expand
National Institutes of Health

Related topics

Related topics

33 relations
ADIPOQ geneADIPOQ wt AlleleAlanine Aminotransferase 1, humanAlanine Aminotransferase 2, human
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Broader (2)

carbohydrate biosynthetic processglucose metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Influence of Resveratrol on the Immune Response
Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries, peanuts, rhubarb, and in several other… Expand
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Review
2019
Review
2019
Gluconeogenesis in Cancer: Function and Regulation of PEPCK, FBPase, and G6Pase.
Cancer cells display a high rate of glycolysis in the presence of oxygen to promote proliferation. Gluconeogenesis, the reverse… Expand
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Review
2018
Review
2018
The Pathophysiology of Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women without previously diagnosed diabetes… Expand
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Highly Cited
2010
Highly Cited
2010
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein… Expand
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Review
2005
Review
2005
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular energy status, and recent data… Expand
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Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand
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Highly Cited
2003
Highly Cited
2003
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… Expand
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Highly Cited
2001
Highly Cited
2001
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
When mammals fast, glucose homeostasis is achieved by triggering expression of gluconeogenic genes in response to glucagon and… Expand
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Review
1992
Review
1992
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis.
Understanding the regulation of hepatic glucose metabolism had its foundation in the elucidation of several pathways, but recent… Expand
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