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A compelling set of links between the composition of the gut microbiota, the host diet, and host physiology has emerged. Do these… Expand Metformin is considered to be one of the most effective therapeutics for treating type 2 diabetes because it specifically reduces… Expand Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein… Expand The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular energy status, and recent data… Expand Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… Expand When mammals fast, glucose homeostasis is achieved by triggering expression of gluconeogenic genes in response to glucagon and… Expand Understanding the regulation of hepatic glucose metabolism had its foundation in the elucidation of several pathways, but recent… Expand UNLABELLED
To quantitate hepatic glycogenolysis, liver glycogen concentration was measured with 13C nuclear magnetic resonance… Expand