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Alanine Aminotransferase 2, human

Known as: Glutamic-Pyruvate Transaminase 2, Glutamate Pyruvate Transaminase 2, GPT2 
Alanine aminotransferase 2 (523 aa, ~58 kDa) is encoded by the human GPT2 gene. This protein is involved in both pyruvate biosynthesis and amino acid… Expand
National Institutes of Health

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7 relations
Alanine Aminotransferase 1, humanAlanine TransaminaseEnzyme GeneGPT2 gene
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling
Increased glutamine metabolism is a hallmark of cancer. Mitochondrial glutamic pyruvate transaminase (GPT2) catalyzes the… Expand
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2016
2016
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series
ABSTRACT Glucose and oxygen are two of the most important molecules transferred from mother to fetus during eutherian pregnancy… Expand
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2016
2016
Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
SUMMARY Metabolic reprogramming is critical to oncogenesis, but the emergence and function of this profound reorganization remain… Expand
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2015
2015
Acclimation of metabolism to light in A rabidopsis thaliana: the glucose 6‐phosphate/phosphate translocator GPT2 directs metabolic acclimation
Abstract Mature leaves of plants transferred from low to high light typically increase their photosynthetic capacity. In A… Expand
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Highly Cited
2008
Highly Cited
2008
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome.
Chromatin structure is epigenetically altered via covalent modifications of histones to allow for heritable gene regulation… Expand
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Highly Cited
2004
Highly Cited
2004
Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver.
Alanine aminotransferase (ALT) is a widely used index of liver integrity or hepatocellular damage in clinics as well as a key… Expand
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Highly Cited
2002
Highly Cited
2002
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase.
Alanine aminotransferase (ALT) catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and… Expand
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Highly Cited
1997
Highly Cited
1997
Influence of malaria on markers of iron status in children: implications for interpreting iron status in malaria-endemic communities.
To investigate Fe nutritional indices in malaria infection in children, haematology (blood haemoglobin, plasma ferritin… Expand
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Highly Cited
1986
Highly Cited
1986
International Federation of Clinical Chemistry (IFCC) Scientific Committee, Analytical Section: approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of…
 
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1973
1973
The mitochondrial redox state of rat brain.
The use of the glutamate dehydrogenase (EC 1.4.1.3) and β-hydroxybutyrate dehydrogenase (EC 1.1.1.30) reactions for the… Expand
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