Skip to search formSkip to main contentSkip to account menu

Alanine Aminotransferase 2, human

Known as: Glutamic-Pyruvate Transaminase 2, Glutamate Pyruvate Transaminase 2, GPT2 
Alanine aminotransferase 2 (523 aa, ~58 kDa) is encoded by the human GPT2 gene. This protein is involved in both pyruvate biosynthesis and amino acid… 
National Institutes of Health

Related topics

Related topics

7 relations
Alanine Aminotransferase 1, humanAlanine TransaminaseEnzyme GeneGPT2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Enhanced glutamine utilization mediated by SLC1A5 and GPT2 is an essential metabolic feature of colorectal signet ring cell carcinoma with therapeutic potential
Background Colorectal signet-ring cell carcinoma (SRCC) is characterized as a rare subset of colorectal cancer with extremely… 
2017
2017
Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling
Increased glutamine metabolism is a hallmark of cancer. Mitochondrial glutamic pyruvate transaminase (GPT2) catalyzes the… 
Highly Cited
2016
Highly Cited
2016
Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
Highly Cited
2016
Highly Cited
2016
Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
Metabolic networks are highly connected and complex, but a single enzyme, O-GlcNAc transferase (OGT) can sense the availability… 
2016
2016
Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features
Significance We report autosomal recessive mutations in the enzyme glutamate pyruvate transaminase 2 (GPT2) in a neurological… 
Highly Cited
2015
Highly Cited
2015
Acclimation of metabolism to light in A rabidopsis thaliana: the glucose 6‐phosphate/phosphate translocator GPT2 directs metabolic acclimation
Abstract Mature leaves of plants transferred from low to high light typically increase their photosynthetic capacity. In A… 
2013
2013
Year-to-year variability in haemoglobin mass response to two altitude training camps
Aim To quantify the year-to-year variability of altitude-induced changes in haemoglobin mass (Hbmass) in elite team-sport… 
Highly Cited
1986
Highly Cited
1986
International Federation of Clinical Chemistry (IFCC) Scientific Committee, Analytical Section: approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of…
Highly Cited
1973
Highly Cited
1973
THE MITOCHONDRIAL REDOX STATE OF RAT BRAIN
The use of the glutamate dehydrogenase (EC 1.4.1.3) and β‐hydroxybutyrate dehydrogenase (EC 1.1.1.30) reactions for the… 
1971
1971
Inhibition by homocysteine of serine dehydratase and other pyridoxal 5'-phosphate enzymes of the rat through cofactor blockage.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)